{"title":"c端胆囊收缩素片段对大鼠循环系统的影响。","authors":"R J Wiśniewska, G Kupryszewski","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The effects of C-terminal unsulfated cholecystokinin octapeptide (CCK-8US) and its fragments C-terminal heptapeptide (CCK-7), C-terminal hexapeptide (CCK-6) and C-terminal pentapeptide (CCK-5) were studied on the arterial blood pressure and the isolated rat heart. CCK-8US had only slight hypertensive and no cardiac effects. CCK-5, CCK-6 and CCK-7 had no effect on the arterial blood pressure, the cardiac contraction amplitude and the heart rate. Only CCK-7 increased coronary outflow of the isolated rat heart. CCK-8US and C-terminal fragments; CCK-7 have little effect on the circulation of the rat.</p>","PeriodicalId":20276,"journal":{"name":"Polish journal of pharmacology and pharmacy","volume":"44 3","pages":"281-7"},"PeriodicalIF":0.0000,"publicationDate":"1992-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The influence of C-terminal cholecystokinin fragments in the circulatory system of rats.\",\"authors\":\"R J Wiśniewska, G Kupryszewski\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The effects of C-terminal unsulfated cholecystokinin octapeptide (CCK-8US) and its fragments C-terminal heptapeptide (CCK-7), C-terminal hexapeptide (CCK-6) and C-terminal pentapeptide (CCK-5) were studied on the arterial blood pressure and the isolated rat heart. CCK-8US had only slight hypertensive and no cardiac effects. CCK-5, CCK-6 and CCK-7 had no effect on the arterial blood pressure, the cardiac contraction amplitude and the heart rate. Only CCK-7 increased coronary outflow of the isolated rat heart. CCK-8US and C-terminal fragments; CCK-7 have little effect on the circulation of the rat.</p>\",\"PeriodicalId\":20276,\"journal\":{\"name\":\"Polish journal of pharmacology and pharmacy\",\"volume\":\"44 3\",\"pages\":\"281-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1992-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Polish journal of pharmacology and pharmacy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polish journal of pharmacology and pharmacy","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The influence of C-terminal cholecystokinin fragments in the circulatory system of rats.
The effects of C-terminal unsulfated cholecystokinin octapeptide (CCK-8US) and its fragments C-terminal heptapeptide (CCK-7), C-terminal hexapeptide (CCK-6) and C-terminal pentapeptide (CCK-5) were studied on the arterial blood pressure and the isolated rat heart. CCK-8US had only slight hypertensive and no cardiac effects. CCK-5, CCK-6 and CCK-7 had no effect on the arterial blood pressure, the cardiac contraction amplitude and the heart rate. Only CCK-7 increased coronary outflow of the isolated rat heart. CCK-8US and C-terminal fragments; CCK-7 have little effect on the circulation of the rat.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
