类器官技术的研究与启示

M. L. Rolim Neto, Giovana Macêdo Egídio Cavalcante
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引用次数: 0

摘要

背景:诱导多能干细胞(iPSC)形成类器官是一项正在研究的新技术,旨在改善各种疾病患者甚至接受某些类型手术的患者的临床状况。方法:采用PRISMA方案进行系统评价。研究时间为2010年至2020年,关键词为“类器官”、“iPSC”、“伦理”和“循证医学”,每次一个,然后结合布尔运算符“and”。结果:共登记44例。在这一总数中,有15篇文章被排除,因为它们没有客观地讨论类器官和干细胞,经常关注其他现象或细节,而这些现象或细节对综述不感兴趣。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Research and Implications of Organoid Technology
Background: The induction of the formation of organoids derived from induced pluripotent stem cells (iPSC) is a new technology that is being well studied and aims to improve the clinical condition of patients with various diseases and even patients undergoing certain types of procedures. Methods: Systematic review, using the PRISMA protocol. The study period was from 2010 to 2020 and the keywords included “Organoids”, “iPSC”, “Ethic” and “Evidence-Based Medicine”, one at a timeand then combined with the Boolean operator “AND”. Results: 44 registrations were found. Of this total, 15 articles were excluded because they have not approached organoids and stem cells objectively, often attending to other phenomena or details that are not of interest to the review.
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