Fulsen Bozkuş, Gogus Hastaliklari Anabilim Dali Kahramanmaras Sutcu Ima Fakultesi
{"title":"肥胖和哮喘","authors":"Fulsen Bozkuş, Gogus Hastaliklari Anabilim Dali Kahramanmaras Sutcu Ima Fakultesi","doi":"10.5152/gghs.2020.021","DOIUrl":null,"url":null,"abstract":"The scientists also found higher concentrations of two asthma-related compounds in the plasma of obese and morbidly obese patients: MMP-9, which is associated with inflammation, and nitric oxide metabolites (NOM), which are an indicator of oxidative stress. Following gastric bypass surgery in morbidly obese diabetic patients, MMP-9 and NOM levels dropped, along with the expression of six asthma-related genes including the key factors, interleukin 4, LIGHT, lymphotoxin? and interleukin 33 in parallel with weight loss and improvements in the status of their diabetes.","PeriodicalId":277627,"journal":{"name":"Güncel Göğüs Hastalıkları Serisi","volume":"26 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Obesity and Asthma\",\"authors\":\"Fulsen Bozkuş, Gogus Hastaliklari Anabilim Dali Kahramanmaras Sutcu Ima Fakultesi\",\"doi\":\"10.5152/gghs.2020.021\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The scientists also found higher concentrations of two asthma-related compounds in the plasma of obese and morbidly obese patients: MMP-9, which is associated with inflammation, and nitric oxide metabolites (NOM), which are an indicator of oxidative stress. Following gastric bypass surgery in morbidly obese diabetic patients, MMP-9 and NOM levels dropped, along with the expression of six asthma-related genes including the key factors, interleukin 4, LIGHT, lymphotoxin? and interleukin 33 in parallel with weight loss and improvements in the status of their diabetes.\",\"PeriodicalId\":277627,\"journal\":{\"name\":\"Güncel Göğüs Hastalıkları Serisi\",\"volume\":\"26 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-09-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Güncel Göğüs Hastalıkları Serisi\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5152/gghs.2020.021\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Güncel Göğüs Hastalıkları Serisi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5152/gghs.2020.021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The scientists also found higher concentrations of two asthma-related compounds in the plasma of obese and morbidly obese patients: MMP-9, which is associated with inflammation, and nitric oxide metabolites (NOM), which are an indicator of oxidative stress. Following gastric bypass surgery in morbidly obese diabetic patients, MMP-9 and NOM levels dropped, along with the expression of six asthma-related genes including the key factors, interleukin 4, LIGHT, lymphotoxin? and interleukin 33 in parallel with weight loss and improvements in the status of their diabetes.