我们能否提前预测心脏手术后第二天谁会从重症监护病房出院

L. Careddu, G. Barberio, L. Marco, I. Cattabriga, Matilde Santia, G. Frascaroli, A. Leone, R. Bartolomeo, D. Pacini
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摘要

导读:大多数接受心脏手术的病人在手术后的第二天就出院了。本研究的目的是评估心脏手术患者延长重症监护病房时间(重症监护病房时间大于1天)的术前、术中和术后早期危险因素。材料和方法:本回顾性研究调查了2182例连续手术患者延长重症监护病房住院时间的决定因素。进行了单变量和多变量分析。结果:46.76%的患者延长了重症监护病房的住院时间。多因素分析显示:术前:年龄(p = 0.001)、慢性阻塞性肺疾病(p = 0.049)、血清肌酐(p = 0.003)、血清总胆红素(p = 0.048)、需要透析的慢性肾功能衰竭(p = 0.040)、静脉输注硝酸盐(p = 0.014)、NYHAⅲ级(p = 0.032)、左心室射血分数(p = 0.006)。术中:主动脉交叉夹持时间(p = 0.04)、CPB持续时间(p < 0.0001)、CPB最低红细胞压比(p < 0.0001)、手术类型(p = 0.012)、CPB后大剂量儿茶酚胺治疗(p = 0.001)。术后:再次探查(p < 0.0001),大量输血(p < 0.0001), ICU入院时动脉pH (p = 0.024)。结论:由于需要心脏手术的高危患者越来越多,确定延长重症监护病房住院时间的危险因素是很重要的。这可以应用于心脏手术患者的调度,以及在资源有限的情况下优化重症监护病房资源规划。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Can we Make an Early Prediction of who will be Discharged from the Intensive Care Unit the Day After Heart Surgery
Introduction: Most of the patients undergoing heart operation are discharged from the intensive care unit the day after their operation. The aim of this study was to evaluate preoperative, intraoperative and early postoperative risk factors for prolonged intensive care unit length of stay (intensive care unit stay greater than 1 day) in cardiac surgery patients. Materials and Methodology: This retrospective study examines the determinants of prolonged intensive care unit length of stay in 2182 consecutive surgical patients. Univariate and multivariate analyses have been performed. Results: 46.76% of all patients had a prolonged intensive care unit length of stay. Multivariate analysis revealed the following independent predictors for prolonged intensive care unit length of stay: Preoperative: Age (p = 0.001), chronic obstructive pulmonary disease (p = 0.049), serum creatinine (p = 0.003), serum total bilirubin (p = 0.048), chronic renal failure requiring dialysis (P = 0.040), intravenous infusion of nitrates (p = 0.014), NYHA class � 3 (p = 0.032), left ventricular ejection fraction (p = 0.006). Intraoperative: aortic cross-clamping time (p = 0.04), CPB duration (P < 0.0001), lowest hematocrit on CPB (p < 0.0001), type of operation (p = 0.012), high doses of catecholamine therapy after CPB (p = 0.001). Postoperative: re-exploration (p < 0.0001), massive transfusions (p < 0.0001), arterial pH at ICU admission (p = 0.024). Conclusion: Due to the increasing number of high-risk patients needing cardiac surgery, it is important to identify risk factors for a prolonged intensive care unit length of stay. This can be applied for scheduling patients for cardiac surgery as well as in optimizing intensive care unit resource planning when resources are limited.
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