LQTS患者RR间期和心电图波幅的不对称性

2022 12th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) Pub Date : 2022-10-09 DOI:10.1109/ESGCO55423.2022.9931345

M. Andrzejewska, Mateusz Ozimek, Karolina Rams, T. Buchner

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引用次数: 1

摘要

一个对刺激反应强烈的系统在时间上更不对称。我们在来自THEW数据库的67名长QT综合征(LQTS)患者和128名健康对照中发现了这种效应，包括RR间隔以及心电图QRS和T复合体的振幅。我们认为，这反映了在这种病理中，心脏效应物对肌力和变时性控制的反应减弱。基于连续节拍之间的振幅差来测量是最好的，尤其是D指数(Hou等)，它利用了成对变量之间很少的重叠。临床相关性-临床不对称指标可区分LQTS患者与健康人群，并可用于LQTS患者及其他心律失常威胁患者的风险分层

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Asymmetry of RR intervals and ECG amplitudes in LQTS patients

A system which responds strongly to stimuli is more asymmetric in time. We show this effect in RR intervals and also in amplitudes of QRS and T complex of the ECG in the groups of 67 long QT syndrome (LQTS) patients and 128 healthy controls from THEW database. We claim that it reflects a diminished response to inotropic and chronotropic control of cardiac effector in this pathology. Measured based on difference of amplitudes between consecutive beats are the best, especially the D index (Hou et al.), which utilizes poor overlap between paired variables. Clinical Relevance-Clinical indices of asymmetry differen-tiate between LQTS and healthy individuals and may be used to stratify risk in LQTS and other patients threatened by arrhythmia

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来源期刊

2022 12th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)

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