Toygün Anıl Özesen, K. Kaya, Mehmet Ali Malkoç, Mete Korkut Gülmen
{"title":"导致死亡的树:紫杉果","authors":"Toygün Anıl Özesen, K. Kaya, Mehmet Ali Malkoç, Mete Korkut Gülmen","doi":"10.17986/blm.1554","DOIUrl":null,"url":null,"abstract":"Yew fruit can cause a large number of human and animal poisoning and can be highly toxic. This is achieved by the taxon alkaloids (Taxin A and Taxin B) that cause cardiotoxic effects in its structure. Taxins cause cardiac dysrhythmia with the effect of calcium channel antagonism in cardiac myocytes and cause a clinical deterioration leading to death. The diagnosis of yew fruit poisoning is usually made by identifying plant parts in the digestive system. With the recent technological developments and the development of toxicological diagnosis methods, the diagnosis of metabolites in lower doses has begun to be made more easily with clinical suspicion.","PeriodicalId":217673,"journal":{"name":"The Bulletin of Legal Medicine","volume":"95 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Tree That Leads to Death: Yew Fruit\",\"authors\":\"Toygün Anıl Özesen, K. Kaya, Mehmet Ali Malkoç, Mete Korkut Gülmen\",\"doi\":\"10.17986/blm.1554\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Yew fruit can cause a large number of human and animal poisoning and can be highly toxic. This is achieved by the taxon alkaloids (Taxin A and Taxin B) that cause cardiotoxic effects in its structure. Taxins cause cardiac dysrhythmia with the effect of calcium channel antagonism in cardiac myocytes and cause a clinical deterioration leading to death. The diagnosis of yew fruit poisoning is usually made by identifying plant parts in the digestive system. With the recent technological developments and the development of toxicological diagnosis methods, the diagnosis of metabolites in lower doses has begun to be made more easily with clinical suspicion.\",\"PeriodicalId\":217673,\"journal\":{\"name\":\"The Bulletin of Legal Medicine\",\"volume\":\"95 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Bulletin of Legal Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17986/blm.1554\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Bulletin of Legal Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17986/blm.1554","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Yew fruit can cause a large number of human and animal poisoning and can be highly toxic. This is achieved by the taxon alkaloids (Taxin A and Taxin B) that cause cardiotoxic effects in its structure. Taxins cause cardiac dysrhythmia with the effect of calcium channel antagonism in cardiac myocytes and cause a clinical deterioration leading to death. The diagnosis of yew fruit poisoning is usually made by identifying plant parts in the digestive system. With the recent technological developments and the development of toxicological diagnosis methods, the diagnosis of metabolites in lower doses has begun to be made more easily with clinical suspicion.