{"title":"氧化钴纳米颗粒的毒性","authors":"Valeta Rebello, S. Shaikh, P. V. Desai","doi":"10.1109/ICEEA.2010.5596127","DOIUrl":null,"url":null,"abstract":"The cytotoxicity of CoO nanoparticles on two micro algae (Navicula sp. and Chetoceros sp.) and Bivalve Gill cells was investigated. Cytotoxicity was determined by cellular morphological changes and LDH (Lactose Dehydrogenase), AP (Acid phosphatase) assays. It is observed that CoO nanoparticles have a detrimental effect on microalgae, promoting shrinkage and cell death. There was a significant increase in percentage of cell death when microalgae were exposed to different concentrations of CoO Nanoparticles. Increase in cell death was accompanied by elevation in LDH and acid phosphatase release indicating cell necrosis/cell injuries. Cell Necrosis was observed when Bivalve gill cells were exposed to different concentrations of CoO Nanoparticles.","PeriodicalId":262661,"journal":{"name":"2010 International Conference on Environmental Engineering and Applications","volume":"83 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2010-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"10","resultStr":"{\"title\":\"Toxicity of cobalt Oxide Nanoparticles\",\"authors\":\"Valeta Rebello, S. Shaikh, P. V. Desai\",\"doi\":\"10.1109/ICEEA.2010.5596127\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The cytotoxicity of CoO nanoparticles on two micro algae (Navicula sp. and Chetoceros sp.) and Bivalve Gill cells was investigated. Cytotoxicity was determined by cellular morphological changes and LDH (Lactose Dehydrogenase), AP (Acid phosphatase) assays. It is observed that CoO nanoparticles have a detrimental effect on microalgae, promoting shrinkage and cell death. There was a significant increase in percentage of cell death when microalgae were exposed to different concentrations of CoO Nanoparticles. Increase in cell death was accompanied by elevation in LDH and acid phosphatase release indicating cell necrosis/cell injuries. Cell Necrosis was observed when Bivalve gill cells were exposed to different concentrations of CoO Nanoparticles.\",\"PeriodicalId\":262661,\"journal\":{\"name\":\"2010 International Conference on Environmental Engineering and Applications\",\"volume\":\"83 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-10-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"10\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2010 International Conference on Environmental Engineering and Applications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/ICEEA.2010.5596127\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2010 International Conference on Environmental Engineering and Applications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICEEA.2010.5596127","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The cytotoxicity of CoO nanoparticles on two micro algae (Navicula sp. and Chetoceros sp.) and Bivalve Gill cells was investigated. Cytotoxicity was determined by cellular morphological changes and LDH (Lactose Dehydrogenase), AP (Acid phosphatase) assays. It is observed that CoO nanoparticles have a detrimental effect on microalgae, promoting shrinkage and cell death. There was a significant increase in percentage of cell death when microalgae were exposed to different concentrations of CoO Nanoparticles. Increase in cell death was accompanied by elevation in LDH and acid phosphatase release indicating cell necrosis/cell injuries. Cell Necrosis was observed when Bivalve gill cells were exposed to different concentrations of CoO Nanoparticles.
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