Gomez Palacios Luna R, Martinez Sofia, Tettamanti Cecilia, Quinteros Daniela, Bracamonte A Guillermo
{"title":"纳米化学和生物偶联与纳米免疫平台,疫苗和新的组合治疗设计的观点","authors":"Gomez Palacios Luna R, Martinez Sofia, Tettamanti Cecilia, Quinteros Daniela, Bracamonte A Guillermo","doi":"10.17352/jvi.000047","DOIUrl":null,"url":null,"abstract":"This Mini-Review and Opinion letter, it was addressed different themes and topics implicated in the development of new treatments and vaccines applied to pathologies developed in humans such as by Virus and related pathogens. In this context, it was presented and discussed different strategies used, which were contemplated from the design of small molecules, towards higher sized chemical structures and new Nanoarchitectures. In particular, it was discussed varied studies developed for the Corona Virus treatment; which afforded to the main mechanisms of action of pharmacophores and targeted functional Nanoparticles. In this direction, it was highlighted the importance of Bioconjugation of molecules and variable Nanoarchitectures for their incorporation within cells as well as for the development of Nano-vaccines. Moreover, it was discussed about the development of combinatory treatments based on different strategies recently reported. Similarly, it was presented different studies and developments actually in progress related to the design of functional and Multifunctional Nano-platforms with potential perspectives on Lab-On particles and Nano-vaccines for precision Nanomedicine and new treatments.","PeriodicalId":330981,"journal":{"name":"Journal of Vaccines and Immunology","volume":"13 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Nano-chemistry and Bio-conjugation with perspectives on the design of Nano-Immune platforms, vaccines and new combinatorial treatments\",\"authors\":\"Gomez Palacios Luna R, Martinez Sofia, Tettamanti Cecilia, Quinteros Daniela, Bracamonte A Guillermo\",\"doi\":\"10.17352/jvi.000047\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This Mini-Review and Opinion letter, it was addressed different themes and topics implicated in the development of new treatments and vaccines applied to pathologies developed in humans such as by Virus and related pathogens. In this context, it was presented and discussed different strategies used, which were contemplated from the design of small molecules, towards higher sized chemical structures and new Nanoarchitectures. In particular, it was discussed varied studies developed for the Corona Virus treatment; which afforded to the main mechanisms of action of pharmacophores and targeted functional Nanoparticles. In this direction, it was highlighted the importance of Bioconjugation of molecules and variable Nanoarchitectures for their incorporation within cells as well as for the development of Nano-vaccines. Moreover, it was discussed about the development of combinatory treatments based on different strategies recently reported. Similarly, it was presented different studies and developments actually in progress related to the design of functional and Multifunctional Nano-platforms with potential perspectives on Lab-On particles and Nano-vaccines for precision Nanomedicine and new treatments.\",\"PeriodicalId\":330981,\"journal\":{\"name\":\"Journal of Vaccines and Immunology\",\"volume\":\"13 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-12-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Vaccines and Immunology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17352/jvi.000047\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Vaccines and Immunology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17352/jvi.000047","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Nano-chemistry and Bio-conjugation with perspectives on the design of Nano-Immune platforms, vaccines and new combinatorial treatments
This Mini-Review and Opinion letter, it was addressed different themes and topics implicated in the development of new treatments and vaccines applied to pathologies developed in humans such as by Virus and related pathogens. In this context, it was presented and discussed different strategies used, which were contemplated from the design of small molecules, towards higher sized chemical structures and new Nanoarchitectures. In particular, it was discussed varied studies developed for the Corona Virus treatment; which afforded to the main mechanisms of action of pharmacophores and targeted functional Nanoparticles. In this direction, it was highlighted the importance of Bioconjugation of molecules and variable Nanoarchitectures for their incorporation within cells as well as for the development of Nano-vaccines. Moreover, it was discussed about the development of combinatory treatments based on different strategies recently reported. Similarly, it was presented different studies and developments actually in progress related to the design of functional and Multifunctional Nano-platforms with potential perspectives on Lab-On particles and Nano-vaccines for precision Nanomedicine and new treatments.