纳米化学和生物偶联与纳米免疫平台,疫苗和新的组合治疗设计的观点

Gomez Palacios Luna R, Martinez Sofia, Tettamanti Cecilia, Quinteros Daniela, Bracamonte A Guillermo
{"title":"纳米化学和生物偶联与纳米免疫平台,疫苗和新的组合治疗设计的观点","authors":"Gomez Palacios Luna R, Martinez Sofia, Tettamanti Cecilia, Quinteros Daniela, Bracamonte A Guillermo","doi":"10.17352/jvi.000047","DOIUrl":null,"url":null,"abstract":"This Mini-Review and Opinion letter, it was addressed different themes and topics implicated in the development of new treatments and vaccines applied to pathologies developed in humans such as by Virus and related pathogens. In this context, it was presented and discussed different strategies used, which were contemplated from the design of small molecules, towards higher sized chemical structures and new Nanoarchitectures. In particular, it was discussed varied studies developed for the Corona Virus treatment; which afforded to the main mechanisms of action of pharmacophores and targeted functional Nanoparticles. In this direction, it was highlighted the importance of Bioconjugation of molecules and variable Nanoarchitectures for their incorporation within cells as well as for the development of Nano-vaccines. Moreover, it was discussed about the development of combinatory treatments based on different strategies recently reported. Similarly, it was presented different studies and developments actually in progress related to the design of functional and Multifunctional Nano-platforms with potential perspectives on Lab-On particles and Nano-vaccines for precision Nanomedicine and new treatments.","PeriodicalId":330981,"journal":{"name":"Journal of Vaccines and Immunology","volume":"13 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Nano-chemistry and Bio-conjugation with perspectives on the design of Nano-Immune platforms, vaccines and new combinatorial treatments\",\"authors\":\"Gomez Palacios Luna R, Martinez Sofia, Tettamanti Cecilia, Quinteros Daniela, Bracamonte A Guillermo\",\"doi\":\"10.17352/jvi.000047\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This Mini-Review and Opinion letter, it was addressed different themes and topics implicated in the development of new treatments and vaccines applied to pathologies developed in humans such as by Virus and related pathogens. In this context, it was presented and discussed different strategies used, which were contemplated from the design of small molecules, towards higher sized chemical structures and new Nanoarchitectures. In particular, it was discussed varied studies developed for the Corona Virus treatment; which afforded to the main mechanisms of action of pharmacophores and targeted functional Nanoparticles. In this direction, it was highlighted the importance of Bioconjugation of molecules and variable Nanoarchitectures for their incorporation within cells as well as for the development of Nano-vaccines. Moreover, it was discussed about the development of combinatory treatments based on different strategies recently reported. Similarly, it was presented different studies and developments actually in progress related to the design of functional and Multifunctional Nano-platforms with potential perspectives on Lab-On particles and Nano-vaccines for precision Nanomedicine and new treatments.\",\"PeriodicalId\":330981,\"journal\":{\"name\":\"Journal of Vaccines and Immunology\",\"volume\":\"13 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-12-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Vaccines and Immunology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17352/jvi.000047\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Vaccines and Immunology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17352/jvi.000047","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3

摘要

这封小型审查和意见信涉及不同的主题和议题,涉及开发适用于病毒和相关病原体等人类病理的新疗法和疫苗。在此背景下,本文提出并讨论了不同的策略,从小分子的设计,到更高尺寸的化学结构和新的纳米结构。特别讨论了为治疗冠状病毒而开展的各种研究;给出了药物团和靶向功能纳米粒子的主要作用机制。在这个方向上,强调了分子的生物偶联和可变纳米结构对其在细胞内结合以及纳米疫苗开发的重要性。并对近年来报道的不同治疗策略的联合治疗进展进行了讨论。同样,会议还介绍了与设计功能性和多功能纳米平台有关的实际进行中的不同研究和发展情况,这些研究和发展可能会对用于精密纳米医学和新疗法的实验室颗粒和纳米疫苗产生影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nano-chemistry and Bio-conjugation with perspectives on the design of Nano-Immune platforms, vaccines and new combinatorial treatments
This Mini-Review and Opinion letter, it was addressed different themes and topics implicated in the development of new treatments and vaccines applied to pathologies developed in humans such as by Virus and related pathogens. In this context, it was presented and discussed different strategies used, which were contemplated from the design of small molecules, towards higher sized chemical structures and new Nanoarchitectures. In particular, it was discussed varied studies developed for the Corona Virus treatment; which afforded to the main mechanisms of action of pharmacophores and targeted functional Nanoparticles. In this direction, it was highlighted the importance of Bioconjugation of molecules and variable Nanoarchitectures for their incorporation within cells as well as for the development of Nano-vaccines. Moreover, it was discussed about the development of combinatory treatments based on different strategies recently reported. Similarly, it was presented different studies and developments actually in progress related to the design of functional and Multifunctional Nano-platforms with potential perspectives on Lab-On particles and Nano-vaccines for precision Nanomedicine and new treatments.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信