ICU临床医生对机器学习和机械通气预测工具实施的看法:单中心调查研究

E. Mlodzinski, G. Wardi, S. Nemati, L. C. Crotty Alexander, A. Malhotra
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The survey consisted of 6 multiple choice and 2 free response questions, with an ordinal scale of 1-5 used in perception-based questions. The survey was designed in accordance with international recommendations for web-based surveys. Our survey was reviewed for completeness by a team of critical care, machine learning, and implementation science experts. Data were collected over a 2- week period in May of 2021. This survey was anonymous and exempt from IRB review. Results Fifty-three critical care physicians (53.5% of providers contacted) started the survey, and of these, 88.7% (47/53) completed the survey. Fifty-nine percent (n=31) of respondents were attendings, 36% (n=19) fellows, and 3.7% (n=2) residents. Baseline knowledge of ML was low (mean= 2.40/5), with only 7.5% (n=4) of respondents rating their knowledge as a 4 or 5. Fifteen percent (n=8) had knowingly used an ML-based tool in their clinical practice. 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引用次数: 0

摘要

尽管人们对机器学习(ML)算法改善患者护理有相当大的兴趣,但这些算法在实践中的实施受到限制。我们的团队开发并验证了一种深度学习算法,用于预测重症监护病房(ICU)患者(包括COVID-19患者)需要机械通气的呼吸衰竭。为了帮助优化该工具的实施,我们开发并传播了一项调查,评估ICU医生对该工具在我们机构的可接受性和可行性的看法。方法采用电子邮件的方式对我院99名重症监护学员和教师进行问卷调查。调查由6道选择题和2道自由回答题组成,感知题采用1-5分的顺序量表。这项调查是根据网络调查的国际建议设计的。我们的调查由一个由重症监护、机器学习和实施科学专家组成的团队审查,以确保完整性。数据收集于2021年5月,为期两周。这项调查是匿名的,不受IRB审查。结果53名重症医师(53.5%)开始了调查,其中88.7%(47/53)完成了调查。59% (n=31)的受访者是主治医生,36% (n=19)的研究员,3.7% (n=2)的住院医生。ML的基线知识很低(平均值= 2.40/5),只有7.5% (n=4)的受访者将自己的知识评为4或5。15% (n=8)在临床实践中故意使用基于ml的工具。预测因COVID-19导致的机械通气需求的置信度(平均值=3.57/5)略低于所有其他原因导致的呼吸衰竭(平均值=3.89/5)。使用基于ml的算法的总体意愿是有利的(平均值=3.32/5)。最有可能增加使用可能性的因素是“高质量的证据表明它优于训练有素的临床医生”(平均=4.28/5),“使用数据的透明度”(平均= 4.13/5)和“有限的工作流程中断”(平均=4.09/5)。参与者的共同担忧包括“闹钟疲劳”和“工作流程中断”。结论ICU医生对基于ml的工具的接触有限,但认为该工具在预测ICU患者和COVID-19患者对机械通气的需求方面是有益的。对于受访者来说,工具的有效性和数据透明度的证据是高度优先考虑的,并且存在对工作流程中断的担忧。这项调查提供了医生接受一种新型基于ml的工具的基线评估,这对于优化其在我们机构的临床实践中的实施至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ICU Clinician Perspectives on Machine Learning and the Implementation of a Mechanical Ventilation Prediction Tool: A Single Center Survey Study
Rationale Although there is considerable interest in machine learning (ML) algorithms to improve patient care, implementation of these algorithms into practice has been limited. Our team developed and validated a deep learning algorithm to predict respiratory failure requiring mechanical ventilation in patients in the intensive care unit (ICU), including those with COVID-19. To help optimize implementation of this tool, we developed and disseminated a survey assessing ICU physician perspectives on the acceptability and feasibility of this tool at our institution. Methods We distributed an 8-item survey to 99 critical care trainees and faculty at our institution via email. The survey consisted of 6 multiple choice and 2 free response questions, with an ordinal scale of 1-5 used in perception-based questions. The survey was designed in accordance with international recommendations for web-based surveys. Our survey was reviewed for completeness by a team of critical care, machine learning, and implementation science experts. Data were collected over a 2- week period in May of 2021. This survey was anonymous and exempt from IRB review. Results Fifty-three critical care physicians (53.5% of providers contacted) started the survey, and of these, 88.7% (47/53) completed the survey. Fifty-nine percent (n=31) of respondents were attendings, 36% (n=19) fellows, and 3.7% (n=2) residents. Baseline knowledge of ML was low (mean= 2.40/5), with only 7.5% (n=4) of respondents rating their knowledge as a 4 or 5. Fifteen percent (n=8) had knowingly used an ML-based tool in their clinical practice. Confidence in predicting the need for mechanical ventilation due to COVID-19 (mean=3.57/5) was slightly lower than for respiratory failure due to all other causes (mean=3.89/5). Overall willingness to utilize an ML-based algorithm was favorable (mean=3.32/5). Factors most likely to increase likelihood of utilization were “high quality evidence that it outperformed trained clinicians” (mean=4.28/5), “transparency of the data utilized” (mean= 4.13/5), and “limited workflow interruption” (mean=4.09/5). Shared concerns from participants included “alarm fatigue” and “workflow interruption.” Conclusion The results suggest that ICU physicians have had limited exposure to ML-based tools, but feel such a tool would be beneficial in the context of predicting need for mechanical ventilation in ICU patients and those with COVID-19. Evidence of the tool's efficacy and data transparency were high priorities for respondents, and there was concern over workflow interruptions. This survey provided a baseline assessment of physician acceptance of a novel ML-based tool, which will be crucial in optimizing its implementation into clinical practice at our institution.
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