俄罗斯新西伯利亚国营服务机构治疗酒精使用障碍患者的病因特异性死亡率

Yaroslav Shamsutdinov, M. Neufeld, J. Rehm
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引用次数: 2

摘要

目的:分析在俄罗斯新西伯利亚国立成瘾治疗中心登记的酒精使用障碍(AUDs)患者样本中死亡年龄和死因特异性死亡率的差异。方法:数据库:2000年至2010年期间新西伯利亚医疗机构记录的92,269例死亡,包括死亡原因(按ICD-10)、性别、出生和死亡日期。研究人员比较了作为初级诊断接受AUDs治疗的患者(n =1,762)与普通人群(后者来自所有医疗机构记录的死亡人数)之间的平均死亡年龄和死因特异性死亡比例。结果:与普通人群相比,患者的平均死亡年龄显著降低(p < 0.001);男性平均少活8.4年;对于女性来说,这个差距是19.7岁。在患者样本中,一般人群(12.7岁)明显的死亡年龄性别差距消失了。他们死于传染病、受伤、中毒、消化系统疾病和某些心血管疾病(如心肌病)的比例更高。他们死于慢性缺血性心脏病、心肌梗死、脑血管疾病和肿瘤的比例更低。结论:与一般人群相比,AUD患者的病因特异性死亡率在很大程度上导致过早死亡。应优先采取具体措施,包括在初级卫生保健中筛查酒精问题和早期干预措施,以减少饮酒量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cause-specific Mortality in Patients Treated for Alcohol Use Disorders in State-Run Services in Novosibirsk, Russia
Aims: To analyze disparities in age at death and cause-specific mortality in a sample of patients registered with alcohol use disorders (AUDs) in state-run addiction treatment centers in Novosibirsk, Russia. Methods: Database: 92,269 deaths recorded by medical facilities in Novosibirsk between 2000 and 2010, comprising cause of death (per ICD-10), sex, and date of birth and death. Average age at death and proportion of cause-specific deaths were compared between patients (n =1,762) treated for AUDs as a primary diagnosis and the general population, the latter derived from deaths recorded by all medical facilities.Results: The average age at death was significantly lower (p < .001) in patients compared with the general population; men lived, on average, 8.4 years fewer; for women, this difference was 19.7 years. The pronounced gender gap in age at death in the general population (12.7 years) disappeared in the patient sample. They incurred proportionally more deaths because of infectious diseases, injuries, poisonings, diseases of the digestive system, and certain cardiovascular diseases such as cardiomyopathies. They incurred proportionally fewer deaths due to chronic ischemic heart disease, myocardial infarction, cerebrovascular diseases, and neoplasms.Conclusions: Compared to the general population, cause-specific mortality in AUD patients was high in categories largely contributing to a premature death. Specific measures including screenings for alcohol problems in primary health care and early interventions to reduce level of drinking should be a priority.
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