使用抗cd3和葡萄球菌肠毒素在体内激活T细胞。

International journal of cancer. Supplement = Journal international du cancer. Supplement Pub Date : 1992-01-01

J A Bluestone, D S Bruce, K A Newell

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摘要

临床免疫的主要问题之一是肿瘤和病毒感染细胞的免疫原性不足，无法触发免疫反应。在过去的几年里，我们的实验室已经探索了使用t细胞特异性试剂，包括单克隆抗体(mab)和葡萄球菌肠毒素来增强免疫反应。本报告总结了我们利用这些制剂增强免疫力的努力。

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Activation of T cells in vivo using anti-CD3 and staphylococcal enterotoxins.

One of the major problems in clinical immunity is that neoplastic and virally infected cells are insufficiently immunogenic to trigger an immune response. During the past several years, our laboratory has explored the use of T-cell-specific reagents including monoclonal antibodies (MAbs) and staphylococcal enterotoxins to amplify immune responses. This report summarizes our efforts to augment immunity with these agents.

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International journal of cancer. Supplement = Journal international du cancer. Supplement

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