卢旺达恩戈罗雷罗地区人类免疫缺陷病毒(HIV)阳性青少年和青壮年病毒载量抑制相关因素

Alice Neza, F. Birungi, E. Remera, François Hakizayezu, J. Ntaganira
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引用次数: 0

摘要

背景:最佳的病毒载量抑制源于良好的治疗依从性。病毒载量抑制的优点包括减少病毒传播。然而,在卢旺达,青少年和年轻人的病毒载量抑制已被证明比其他年龄组相对较低。目的评估卢旺达恩戈罗雷罗地区青少年和年轻人病毒载量抑制的相关因素。方法对恩戈罗雷罗地区15 ~ 24岁的151名青少年和青壮年进行横断面研究。数据在Epi-Info version 7软件中输入,并使用STATA15进行分析。结果女性占68%,男性占32%。60%的参与者年龄在20-24岁之间。多变量分析显示与病毒载量抑制相关的因素:Ubudehe 2类,P= 0.016, AOR = 6.6, CI [1.4, 31.1];3类患者,P= 0.004, AOR = 8.9, CI [2.01,39.8];接受抗逆转录病毒治疗5 ~ 9年,P= 0.022, AOR = 0.16 [CI0.03, 0.89];经常忘记服药,P= 0.011, AOR = 0.35, CI[0.13, 0.97]。结论青少年和青壮年的病毒载量抑制程度较低。改善青少年和青壮年的社会经济条件,以及在其整个治疗期间向他们持续提供咨询,可显著提高他们的依从性。卢旺达医学与健康科学杂志,2023;6(1):43-52
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Factors Associated with Viral Load Suppression among Human Immunodeficiency Virus (HIV) Positive Adolescents and Young Adults in Ngororero District, Rwanda
BackgroundOptimal viral load suppression results from good adherence to treatment. The viral load suppression advantages include the reduction of virus transmission. In Rwanda, however, viral load suppression among adolescents and young adults has been proven relatively low than in other age groups.ObjectivesTo assess the factors associated with viral load suppression among adolescent and young adults in Ngororero district, Rwanda.MethodsA cross sectional study that included 151 adolescents and young adults aged from 15 to 24 years was conducted in Ngororero district. Data were entered in Epi-Info version 7 software and analyzed using STATA15.ResultsFemales and males were 68% and 32% respectively. Sixty percent of the participants were aged 20-24 years. Multivariable analysis revealed the factors associated with viral load suppression: Ubudehe category 2, P= 0.016, AOR = 6.6, CI [1.4, 31.1]; ubudehe category 3, P= 0.004, AOR = 8.9, CI [2.01,39.8]; spending between 5 to 9 years on ART, P= 0.022, AOR = 0.16 [CI0.03, 0.89;) and often forget to take medication, P= 0.011, AOR = 0.35, CI [0.13, 0.97.]ConclusionViral load suppression among adolescents and young adults was low. Improving socio-economic conditions of adolescents and young adults, as well as provision of continuous counselling to them during their whole treatment life can improve significantly their adherence.Rwanda J Med Health Sci 2023;6(1):43-52
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