影响糖尿病血液透析患者低血糖发生率的因素

Hongyan Peng, Rui Cao, Yaping Huang, Chazhen Li
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摘要

目的:探讨糖尿病血液透析患者低血糖发生的影响因素。方法:记录2017年5月至2021年2月557例患者的有效资料。本研究分为收集步骤、筛选步骤和分析步骤三个步骤。在收集步骤中,我们的主要任务是从符合条件的患者中收集数据。在筛选阶段,我们根据患者是否发生过低血糖事件,将患者分为低血糖组和非低血糖组。此外,我们将在此阶段排除不合格的患者数据。在分析步骤中,我们使用软件对数据进行分析,并通过多元Logistic回归分析分析相关因素。结果:与非低血糖组比较,我们发现低血糖组影响低血糖事件的4个因素,白蛋白、BMI、年龄、hs-CRP差异有统计学意义(p < 0.05)。其他因素在低血糖组和非低血糖组之间无显著差异。进一步分析,白蛋白、BMI、年龄、hs-CRP是低血糖事件的独立危险因素(p < 0.05)。结论:白蛋白、BMI、年龄、hs-CRP是糖尿病血液透析患者低血糖的影响因素。此外,低血糖事件的独立危险因素包括白蛋白、BMI、年龄和hs-CRP。其中,白蛋白和BMI可以被药物或患者行为控制或影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Factors Influencing the Incidence of Hypoglycemia in Diabetic Hemodialysis Patients
Objective: To explore factors influencing the incidence of hypoglycemia in diabetic hemodialysis patients. Methods: we recorded the valid data from 557 patient from May 2017 to February 2021. This study consists of 3 steps, including collecting step, screening step and analysis step. In collecting step, our mainly task was collecting the data from the eligible patients. In screening step, we assigned patients to hypoglycemia and non-hypoglycemia based on whether they had a hypoglycemic event or not. Also, we will exclude ineligible patient data at this stage. In analysis step, we use software to analyze the data, and analyze related factors by multivariate Logistic regression analysis. Result: Compared with non- hypoglycemia group, we found that four factor of hypoglycemia group affect hypoglycemia event, they were significantly difference, including albumin, BMI, age, and hs-CRP (p < 0.05). Other factors were no significantly difference between hypoglycemia group and non- hypoglycemia group. In further analysis, the result displays that albumin, BMI, age, and hs-CRP were independent risk factors for hypoglycemia event (p < 0.05). Conclusion: albumin, BMI, age, and hs-CRP were impact factors of hypoglycemia in diabetic hemodialysis patients. Furthermore, the independent risk factors of hypoglycemia event included albumin, BMI, age, and hs-CRP. Of those, albumin and BMI can be control or affected by drugs or patient behaviors.
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