肺放射治疗中SBRT和IMRT技术的研究:剂量学研究

E. Ates
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引用次数: 0

摘要

目的:在我们的研究中,我们旨在比较Accuray品牌TomoTherapy设备Volo治疗计划系统肺立体体放射治疗(SBRT)和强度调整放射治疗在使用(IMRT)技术和环境剂量获得的癌症剂量分布。材料与方法:将7例患者的CT图像转移到MIM轮廓站进行剂量测量。CT靶体积图像;PTV右或左肺,关键器官:心脏,costa,食道,髓质,双侧肺转移到规划系统。肺肿瘤是虚拟的。在研究中,1厘米大小的肿瘤形成为厘米、3厘米和5厘米。配偶随肺肿瘤大小变化。随着时间的推移,TomoTherapy设备的横截面(下颌)面积也将分别为1厘米、2.5厘米和5厘米。它已经过修改,并在每种肿瘤大小下进行了SBRT和IMRT技术的测试。结果:建立了PTV剂量治疗方案为60gy,分3段进行治疗。本研究比较了1cm肿瘤大小的SBRT和IMRT技术对肺癌的治疗效果,结果对于1cm颌骨、2.5 cm颌骨和5cm颌骨中1cm肿瘤大小和5cm肿瘤PTV max、D95值用于1cm颌骨大小和双侧,这是关键器官。SBRT组肺max值差异有统计学意义(p < 0.05)。结论:采用1 cm、3 cm和5 cm肿瘤大小分别在1 cm、2.5 cm和5 cm切片(颌)区域,根据两种技术保存关键器官。但SBRT技术在靶体积(PTV)和双肺方面显示出更好的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Investigation of SBRT and IMRT Techniques in Lung Radiotherapy: A Dosimetric Study
Objective: In our study, we aimed to compare the dose distrubutions of Accuray brand TomoTherapy device Volo treatment planning system lung stereoactic body radiation therapy (SBRT) and intensity-adjusted radiation therapy in cancer dose distributions obtained using (IMRT) techniques and environmental doses. Matetial and Method: Computed Tomography (CT) images of 7 patients were transferred to the MIM contouring station for dose measurement. CT target volume via image; PTV right or left lung, critical organs: heart, costa, esophagus, medulla, bilateral lung transferred to planning system. Lung tumors created virtually.In study 1 cm tumor of the size it is formed to be cm,3 cm and 5 cm. Spouse as lungtumor sizes change.in time, the cross-section (jaw) area of the TomoTherapy device will also be 1 cm, 2.5 cm and 5 cm it has been modified and tested for SBRT and IMRT techniques at each tumor size. Results: PTV dose treatment plans have been established to be 60 Gy and 3 fractions. The study 1 cm tumor of the size SBRT and IMRT techniques compared to the treatment of lung cancer as a result for 1 cm jaw, 2.5 cm jaw and 5 cm jaw in cm tumor size and 5 cm tumor PTV max, D95 values for 1 cm jaw used in size and bilateral, which is the critical organs. A significant difference in lung max values was found in favor of SBRT (p<0.05). 3 cm tumor size used in 1 cm, 2.5 cm and 5 cm jaw areas and 5 cm treatment compared to 2.5 and 5 cm jaw areas used in cm tumor bouts statistics on ptv max and bilateral lung max values at the end of the analysis, an agreed difference was found in favor of the SBRT (p<0.05) during treatment periods. At the end of statistical analysis in 1 cm jaw area used in 1 cm tumor size a significant difference in favor of IMRT has been identified.(p<0.05) and no significant differences were found for other critical organs (p > 0.05). Conclusion: As a result, 1 cm, 3 cm and 5 cm tumor sizes used in 1 cm, 2.5 cm and 5 cm section (jaw) areas according to both techniques preserved critical organs. But the SBRT technique showed better results in terms of target volume (PTV) and both lungs.
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