在接受联合抗逆转录病毒治疗的HIV患者中结核病作为机会性感染的发生率

M. Koirala, B. Thapa, B. Tamrakar, Surya Bahadur Hamal, Bishow Raj Baral, B. Lamichanne, A. Nepal, Aarati Acharya, R. Pangeni
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引用次数: 0

摘要

HIV血清转化后活动性肺结核的风险增加。它随着免疫力的下降而逐渐增加。艾滋病毒感染的结核病导致全球结核病发病率急剧上升,导致发病率和死亡率显著增加。许多临床研究表明,结核病是最常见的机会性感染之一。本研究旨在了解接受联合抗逆转录病毒治疗(cART)的HIV患者中结核病作为机会性感染的发生率。材料和方法:这是一项基于医院的横断面比较研究。500名接受cART治疗的艾滋病患者参加了这项研究。结果:500例HIV感染者中,男性266例(53.2%),女性234例(46.68%)。在这些艾滋病患者中,48名男性(18.04%)和17名女性(7.26%)患有结核病。65例(13%)患者同时感染结核/艾滋病毒。男性TB/HIV患者中有2例(4.1%)存在宫颈腺结核。结论:HIV感染者中结核病的发病率较高。结核病是艾滋病毒/艾滋病感染者中最常见的机会性感染。男性是结核/艾滋病毒合并感染的主要性别。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Incidence of Tuberculosis as a Opportunistic Infection in Patients with HIV Getting Combined Anti Retroviral Therapy
Introduction: The risk of active Tuberculosis increases after HIV seroconversion. It progressively increases with declining immunity. Tuberculosis (TB) epidemics in HIV has led to a dramatic upsurge in global TB incidence, resulting in remarkable increase in morbidity and mortality. Many clinical studies had shown that TB is one of the commonest opportunistic infection. This study is conducted to see the incidence of tuberculosis as an opportunistic infection in patients with HIV getting combined antiretroviral therapy (cART) Materials and Methods: This was a hospital based cross-sectional comparative study. Five hundred patients with HIV who are getting cART were enrolled in the study. Results: Analysis of individuals with HIV in our study amongst the 500 patients 266 (53.2%) were males and the remaining 234 (46.68%) were females. Amongst these HIV patients 48(18.04%) males and 17(7.26%) females had tuberculosis. 65(13%) of patients were TB/HIV co-infected. 2(4.1%) of these male TB/HIV patients had cervical gland TB. Conclusion: The incidence of tuberculosis in HIV infected individuals is high. TB is the commonest opportunistic infection (OIs) in people living with HIV/AIDS. Males are predominant gender to have TB/HIV co-infection.
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