老年患者的非特异性慢性腰痛

Amal Mowafy
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摘要

引言:腰痛是老年人致残最常见的原因之一,通常是由于腰椎退行性变(骨关节炎)和椎管狭窄。在我们的研究中,我们确定了随着年龄增长而增加的腰痛的患病率和相关变化。方法:这项观察性队列研究于2019年3月至2021年3月在塞得港的El-Moussenin中心进行。该研究纳入300例年龄≥65岁的慢性非特异性腰痛患者,至少6个月,视觉模拟量表(VAS)评分为3分及以上,无2级及以上脊柱病理,如感染、肿瘤、骨折、脊柱滑脱或脊柱退变。患者被分为两组:(i)研究组包括平均年龄为75岁的非特异性慢性腰痛患者(n = 150)和(ii)年龄和性别匹配的对照组(n = 150),使用倾向评分匹配分析无慢性腰痛。所有患者均行全脊柱x线、腰椎MRI、CBC和DXA检查。结果:我们使用全身双能x线吸收仪分析了实验室发现、整体脊柱参数的放射学发现和木材退变的身体成分分析。我们发现红细胞分布宽度(它是衰老的一个指标)增加,CLBP的老年人(32)和对照组(6.9)的红细胞分布宽度更高,p值< 0.001。研究组骨骼肌质量指数为6.23±0.92,对照组为6.43±1.02,p值= 0.045。研究组(32.17±7.07)和对照组(29.28±7.48)的脂肪量均有所增加,p值< 0.001。此外,这些患者在躯干和四肢的肌肉量减少时出现腰下凸,矢状垂直轴较高。结论:老年CLBP患者红细胞分布宽度较高,是衰老的标志。此外,老年CLBP通常与骨质疏松症有关,骨质疏松症会影响疼痛阈值,并由于骨骼肌质量的年龄相关损失和脊柱矢状位失调而引发CLBP。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nonspecific Chronic Low Back Pain in Elderly Patients
Introduction: Low back pain is one of the most common causes of disabilities in old people often due to lumber degeneration (osteoarthritis) and spinal canal stenosis. In our study, we determine the prevalence and associated changes of low back pain that increase with age. Methodology: This observational cohort study was carried out from March 2019 to March 2021 at the El-Moussenin Center in Port Said. The study included 300 patients aged ≥65 years with a chronic nonspecific low back pain for at least six months, a Visual Analogue Scale (VAS) score of 3 and more, and an absence of spinal pathology such as infection, tumor, fracture, spondylolisthesis, or spinal degeneration of grade 2 and above. Patients were divided into two groups: (i) a study group including patients with a mean age of 75 years with nonspecific chronic LBP (n = 150) and (ii) an age- and sex-matched control group (n = 150) with no chronic low back pain using propensity score-matched analysis. All patients underwent whole spinal X-ray, lumbar MRI, CBC, and DXA. Result: We analyzed laboratory finding, radiological finding for global spinal parameter, and lumber degeneration body composition analysis using whole body dual energy X-ray absorptiometry. We found increase in red blood cell distribution width (it is an index of aging), it was higher in geriatric with CLBP (32) and in control (6.9) with a p-value < 0.001. Skeletal muscle mass index was 6.23 ± 0.92 in the studied group and 6.43 ± 1.02 in the control group with a p-value = 0.045. Increase in fat mass was noted in both the studied (32.17 ± 7.07) and the control (29.28 ± 7.48) groups with a p-value < 0.001. Moreover, those patients had lower lumbar lordosis, higher sagittal vertical axis regarding decrease in muscle mass in trunk and extremities. Conclusion: Red blood cell distribution width which is a sign of aging was high in geriatric group with CLBP. Moreover, geriatric CLBP is often associated with osteoporosis which affects the pain threshold and triggers CLBP due to age-related loss of skeletal muscle mass and spinal sagittal malalignment.
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