{"title":"人工智能在肝癌患者生存预测中的应用","authors":"Kun-Huang Chen, Hui-Wu Wang, Chung-Ming Liu","doi":"10.1145/3417188.3417197","DOIUrl":null,"url":null,"abstract":"Cancer, a disease that has gradually attracted attention in the world now, it has even become one of the main causes of death. Among them, liver cancer occurs in the liver or deadly tumors starting from the liver. According to the World Cancer Report (2014), the liver cancer is primary the cancer that the occurrence of 6% ranked second highest, and the death rate is 9% ranked sixth. So the liver cancer has become the target of academic research and discussion. If we can find out the key factors that affect the death of liver cancer when identifying liver cancer, it can improve the survival prediction of patients with liver cancer, and it will bring more effective treatment and confidence to the disease. In this paper, we chose a data that a real clinically diagnosed HCC patient was collected from a University of Coimbra and Coimbra Hospital in Portugal, and we separated the data into testing and training to predict the death of HCC and find out the key factors from the prediction model. The prediction model includes Decision Tree (DT), Support vector machine (SVM), and Logistic Regression (LR). The results of this paper showed that the G-means of the three modeling methods are 0.76 (LR), 0.72 (DT), and 0.68 (SVM). The best performance is logistic regression (LR), and find out the key factors that affect the survival rate of HCC include Aspartate transaminase (U / L), Age at diagnosis, and Alkaline phosphatase (U / L).","PeriodicalId":373913,"journal":{"name":"Proceedings of the 2020 4th International Conference on Deep Learning Technologies","volume":"75 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Applying Artificial Intelligence to Survival Prediction of Hepatocellular Carcinoma Patients\",\"authors\":\"Kun-Huang Chen, Hui-Wu Wang, Chung-Ming Liu\",\"doi\":\"10.1145/3417188.3417197\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cancer, a disease that has gradually attracted attention in the world now, it has even become one of the main causes of death. Among them, liver cancer occurs in the liver or deadly tumors starting from the liver. According to the World Cancer Report (2014), the liver cancer is primary the cancer that the occurrence of 6% ranked second highest, and the death rate is 9% ranked sixth. So the liver cancer has become the target of academic research and discussion. If we can find out the key factors that affect the death of liver cancer when identifying liver cancer, it can improve the survival prediction of patients with liver cancer, and it will bring more effective treatment and confidence to the disease. In this paper, we chose a data that a real clinically diagnosed HCC patient was collected from a University of Coimbra and Coimbra Hospital in Portugal, and we separated the data into testing and training to predict the death of HCC and find out the key factors from the prediction model. The prediction model includes Decision Tree (DT), Support vector machine (SVM), and Logistic Regression (LR). The results of this paper showed that the G-means of the three modeling methods are 0.76 (LR), 0.72 (DT), and 0.68 (SVM). The best performance is logistic regression (LR), and find out the key factors that affect the survival rate of HCC include Aspartate transaminase (U / L), Age at diagnosis, and Alkaline phosphatase (U / L).\",\"PeriodicalId\":373913,\"journal\":{\"name\":\"Proceedings of the 2020 4th International Conference on Deep Learning Technologies\",\"volume\":\"75 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-07-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the 2020 4th International Conference on Deep Learning Technologies\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1145/3417188.3417197\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 2020 4th International Conference on Deep Learning Technologies","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1145/3417188.3417197","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
摘要
癌症,一种逐渐引起世界关注的疾病,甚至已经成为人类死亡的主要原因之一。其中肝癌发生在肝脏或从肝脏开始的致命肿瘤。根据《世界癌症报告(2014)》,肝癌是原发性癌症,发生率为6%,排名第二高,死亡率为9%,排名第六。因此肝癌已成为学术界研究和讨论的对象。如果我们在鉴别肝癌时能够找出影响肝癌死亡的关键因素,可以提高肝癌患者的生存预测,也会给疾病带来更有效的治疗和信心。在本文中,我们选择了来自葡萄牙科英布拉大学和科英布拉医院的真实临床诊断HCC患者的数据,我们将数据分为测试和训练两部分来预测HCC的死亡,并从预测模型中找出关键因素。预测模型包括决策树(DT)、支持向量机(SVM)和逻辑回归(LR)。结果表明,三种建模方法的g均值分别为0.76 (LR)、0.72 (DT)和0.68 (SVM)。采用logistic回归(LR)分析效果最佳,发现影响HCC生存率的关键因素有天冬氨酸转氨酶(U / L)、诊断时年龄(Age at diagnosis)和碱性磷酸酶(U / L)。
Applying Artificial Intelligence to Survival Prediction of Hepatocellular Carcinoma Patients
Cancer, a disease that has gradually attracted attention in the world now, it has even become one of the main causes of death. Among them, liver cancer occurs in the liver or deadly tumors starting from the liver. According to the World Cancer Report (2014), the liver cancer is primary the cancer that the occurrence of 6% ranked second highest, and the death rate is 9% ranked sixth. So the liver cancer has become the target of academic research and discussion. If we can find out the key factors that affect the death of liver cancer when identifying liver cancer, it can improve the survival prediction of patients with liver cancer, and it will bring more effective treatment and confidence to the disease. In this paper, we chose a data that a real clinically diagnosed HCC patient was collected from a University of Coimbra and Coimbra Hospital in Portugal, and we separated the data into testing and training to predict the death of HCC and find out the key factors from the prediction model. The prediction model includes Decision Tree (DT), Support vector machine (SVM), and Logistic Regression (LR). The results of this paper showed that the G-means of the three modeling methods are 0.76 (LR), 0.72 (DT), and 0.68 (SVM). The best performance is logistic regression (LR), and find out the key factors that affect the survival rate of HCC include Aspartate transaminase (U / L), Age at diagnosis, and Alkaline phosphatase (U / L).