尼日利亚南南三级医疗机构眼科病变模式

K. Inaku, A. Ibanga, A. Omotoso, I. Bassey, S. Okonkwo, M. Kooffreh-Ada, G. Ebughe, Peter Ada
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摘要

目的:眼肿瘤是发生在眼睛及其他相关结构的肿瘤。这些病变涉及范围广泛的病理状况,从良性到恶性病变,在非洲很常见。虽然已经发表了一些关于这个问题的评论,但没有一个是在这种环境下进行的。本研究旨在确定在尼日利亚南部卡拉巴尔报道的眼部肿瘤的模式、患病率和类型。方法:检索卡拉巴大学教学医院病理科2008 - 2016年患者的住院记录,进行分析,获取所需信息。结果:研究期间共诊断眼部肿瘤70例,其中恶性肿瘤占50.0%。男性略多于女性(比例为1.3:1),约占55.7%。眼科恶性肿瘤前三位分别为鳞状细胞癌、视网膜母细胞瘤和胚胎横纹肌肉瘤,分别占所有眼部肿瘤的21.4%、17.1%和5.7%。皮样囊肿是最常见的眼科良性肿瘤(8.5%)。其中,0 ~ 10岁(42.9%)、21 ~ 40岁(43.2%)和41 ~ 50岁(14.3%)为3个癌症发病高峰。视网膜母细胞瘤是儿童中最常见的癌症,成人中最常见的是鳞状细胞癌。结论:本组病例中眼恶性肿瘤与良性肿瘤的发生率相同。诊断延误是一个典型特征。强烈建议尽早到眼科护理机构进行适当的早期干预,以防止潜在的视力丧失甚至死亡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pattern of Ophthalmic Lesions in a Tertiary Health Institution in South-South, Nigeria
Objective: Ophthalmic tumors are tumors that occur in the eyes and other related structures. These lesions involve a wide range of pathologic conditions ranging from benign to malignant lesions and are common in Africa. Although there have been a number of published reviews on this subject, none was carried out in this environment. This study seeks to determine the pattern, prevalence, and types of ophthalmic tumors reported in Calabar, southern Nigeria. Methods: Patient’s hospital records were retrieved from the Department of Pathology, University of Calabar teaching hospital within the period of 2008 to 2016 and analyzed to obtain required information. Results: A total of 70 ophthalmic tumors were diagnosed during the study period of which 50.0% were malignant. Males were slightly more affected than females (ratio 1.3:1) accounting for about 55.7%. The top three ophthalmic malignant tumors were squamous cell carcinoma, retinoblastoma, and embryonal rhabdomyosarcoma contributing 21.4%, 17.1%, and 5.7%, respectively, of all eye tumors. Dermoid cyst (8.5%) was the most common benign ophthalmic tumor reported. In all, three cancer incidence peaks were observed at 0 to 10 (42.9%), 21 to 40 (43.2%), and 41 to 50 (14.3%) age groups. Retinoblastoma was the most common cancer in children and squamous cell carcinoma was commoner among adults. Conclusion: The prevalence of malignant and benign eye tumors was the same in this review. A delay in diagnosis was a characteristic feature. Early presentation to eye-care facilities for appropriate and early intervention is highly recommended to prevent potential loss of eyesight and even death.
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