尼日利亚三角洲州Ukwani和埃塞俄比亚东部地方政府地区非洲人类锥虫病的大规模调查

Musad, A. Fajinmi, R. Abdullahi, A. E. Irhue, I. Toma
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引用次数: 0

摘要

本研究旨在更新尼日利亚Ukwuani和Ethope东部地方政府区(LGAs)三角洲州非洲人类锥虫病(又称昏睡病)的流行病学状况,并制定锥虫病控制规划。2012年,对26个村庄的1979人进行了HAT病原体布氏锥虫病血清学筛查。2012年,在已发现HAT病例的村庄开展了调查。采用卡凝集锥虫病试验(CATT)对119例个体进行筛选,并进行寄生虫学检查。对不能确认寄生虫存在的CATT阳性个体,采用血清稀释法进一步进行CATT检测,对抗体滴度在1 / 4及以上的阳性者进行随访。脑脊液(CSF)中有10个白细胞且无锥虫的患者被归类为该病的第二阶段。病媒控制也被认为是必要的。在这项调查中,在1979人中,1220名女性中有7人(0.57%),759名男性中有4人(0.53%),性别特异性发病率无差异。阳性病例发生在乌库瓦尼地区的Umutu和Umuebu社区,以及埃塞俄比亚东部地区的Ovu和Okpara内陆社区。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mass Survey of Human African Trypanosomiasis in Ukwani and Ethiope East Local Government Areas, Delta State, Nigeria
This study was intended to update the epidemiological status of Human African Trypanosomiasis (HAT), also known as sleeping sickness in Ukwuani and Ethope East Local Government Areas (LGAs) Delta State, Nigeria, and to establish a HAT control programme. In 2012, 1979 people from 26 villages were serologically screened for Trypanosomabruceigambiense, the causative agent of HAT. In 2012, surveys were carried out in villages where HAT cases had been identified. 119individuals were screened using the card agglutination Trypanosomiasis test (CATT), and then parasitologically examined for the presence of the parasite. CATT- positive individuals in whom the presence of the parasite could not be confirmed were further tested with the CATT using serum dilutions, and those with a positive antibody titer of 1 – in – 4or above were followed-up. Patients with 10 white cells and no trypanosomes in their cerebrospinal fluid (CSF) were classified as being in the second stage of the disease. Vector control was also considered necessary.In this survey, of the 1979 people screened, consisting of 7(0.57%) out of 1220 females and 4(0.53%) out of 759 males with no difference in sex – specificincidences. The positive cases occurred in Umutu and Umuebu communities in Ukuwani LGA, and in Ovu and Okpara inland communities in Ethiope- East LGA.
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