百里酚作为抗寄生虫药物的化学成分和生物学意义

W. Hikal, K. Tkachenko, H. Ahl, Hoda Sany, A. Sabra, Rowida S Baeshen, Amra Bratovcic
{"title":"百里酚作为抗寄生虫药物的化学成分和生物学意义","authors":"W. Hikal, K. Tkachenko, H. Ahl, Hoda Sany, A. Sabra, Rowida S Baeshen, Amra Bratovcic","doi":"10.4236/OJE.2021.113018","DOIUrl":null,"url":null,"abstract":"Thymol is one of the most important phytochemical components because of its pharmacological and bioactive potential effects. This review focuses particularly on thymol as an alternative natural antiparasitic with potential use in the pharmaceutical industry. This is in line with the preferences of the natural products for treatment being safer and without side effects. The biosynthesis pathways of thymol and carvacrol have been discussed, and mechanism of action of thymol on parasites. Studies on thymol confirmed the activity of thymol as anti-parasite against anthelmintic, Trypanosoma ssp., Toxoplasma gondii, Leishmania spp., Plasmodium falciparum, Giardia duodenalis, Eimeria ssp., Cryptosporidium baileyi and Cryptosporidium galli.","PeriodicalId":265480,"journal":{"name":"Open Journal of Ecology","volume":"24 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"5","resultStr":"{\"title\":\"Chemical Composition and Biological Significance of Thymol as Antiparasitic\",\"authors\":\"W. Hikal, K. Tkachenko, H. Ahl, Hoda Sany, A. Sabra, Rowida S Baeshen, Amra Bratovcic\",\"doi\":\"10.4236/OJE.2021.113018\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Thymol is one of the most important phytochemical components because of its pharmacological and bioactive potential effects. This review focuses particularly on thymol as an alternative natural antiparasitic with potential use in the pharmaceutical industry. This is in line with the preferences of the natural products for treatment being safer and without side effects. The biosynthesis pathways of thymol and carvacrol have been discussed, and mechanism of action of thymol on parasites. Studies on thymol confirmed the activity of thymol as anti-parasite against anthelmintic, Trypanosoma ssp., Toxoplasma gondii, Leishmania spp., Plasmodium falciparum, Giardia duodenalis, Eimeria ssp., Cryptosporidium baileyi and Cryptosporidium galli.\",\"PeriodicalId\":265480,\"journal\":{\"name\":\"Open Journal of Ecology\",\"volume\":\"24 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-02-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Open Journal of Ecology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4236/OJE.2021.113018\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Journal of Ecology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4236/OJE.2021.113018","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5

摘要

百里酚是最重要的植物化学成分之一,因为它具有潜在的药理和生物活性作用。本综述特别关注百里酚作为一种天然抗寄生虫替代品在制药业的潜在用途。这符合人们对更安全、无副作用的天然产品治疗的偏好。研究讨论了百里酚和香芹酚的生物合成途径,以及百里酚对寄生虫的作用机制。对百里酚的研究证实,百里酚对驱虫药、锥虫、弓形虫、利什曼原虫、恶性疟原虫、十二指肠贾第虫、埃默氏菌、贝利隐孢子虫和加利隐孢子虫具有抗寄生虫活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Chemical Composition and Biological Significance of Thymol as Antiparasitic
Thymol is one of the most important phytochemical components because of its pharmacological and bioactive potential effects. This review focuses particularly on thymol as an alternative natural antiparasitic with potential use in the pharmaceutical industry. This is in line with the preferences of the natural products for treatment being safer and without side effects. The biosynthesis pathways of thymol and carvacrol have been discussed, and mechanism of action of thymol on parasites. Studies on thymol confirmed the activity of thymol as anti-parasite against anthelmintic, Trypanosoma ssp., Toxoplasma gondii, Leishmania spp., Plasmodium falciparum, Giardia duodenalis, Eimeria ssp., Cryptosporidium baileyi and Cryptosporidium galli.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信