缺血性脑卒中患者的血脂异常:来自巴基斯坦一家三级护理教学医院的结果

Ali Hassan Mahesar, M. Soomro, M. Magsi, A. A. Baloch, M. Soomro
{"title":"缺血性脑卒中患者的血脂异常:来自巴基斯坦一家三级护理教学医院的结果","authors":"Ali Hassan Mahesar, M. Soomro, M. Magsi, A. A. Baloch, M. Soomro","doi":"10.4038/jccpsl.v27i3.8409","DOIUrl":null,"url":null,"abstract":"Introduction: Ischaemic stroke is a heterogeneous multifactorial disorder characterized by acute focal neurological deficit due to cerebrovascular disease. Considering the clinical evidence of dyslipidaemia as a risk factor for ischaemic stroke, there is a need to know the magnitude of dyslipidaemia in patients. Aim of the study was to determine the frequency of dyslipidaemia in patients of ischaemic stroke at a tertiary care teaching hospital in Larkana, Pakistan. Methods: A cross-sectional study was conducted at the Department of Medicine, Shaheed Mohtarma Benazir Bhutto Medical University Hospital Larkana, Pakistan during the period of six months (July-December 2016). All patients between 18-75 years of age of either gender suffering from ischaemic stroke were included. All patients with intracranial haemorrhage, CNS tumour, epilepsy, multiple sclerosis, familial lipid disorders, endocrine disorders, chronic diseases, and on anti-lipid medications, cocaine or alcohol addicts were excluded. The statistical analysis was conducted by using Stata Statistical Software 14. Results: Mean age of enrolled participants was 46.3 (SD=15.2) years. Of 85 enrolled participants, 73 (85.9%) were males and 12 (14.1%) were females, with male to female ratio of 6:1. The frequency of dyslipidaemia was 28 (32.9%), with mean LDL 100.7 (SD=18.4) mg/dl and HDL 42 (SD=11.7) mg/dl and total cholesterol 166.3 (SD=34.3) mg/dl. Conclusions & Recommendations: Dyslipidaemia, with low HDL 13 (15.3%) was found to be the most common risk factor we observed in our patients with stroke. The importance of preventive measures for a disease which has modifiable risk factors (diabetes and hypertension) should be emphasized to reduce the burden of stroke in the country.","PeriodicalId":120205,"journal":{"name":"Journal of the College of Community Physicians of Sri Lanka","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Dyslipidaemia in ischaemic stroke patients: results from a tertiary care teaching hospital of Pakistan\",\"authors\":\"Ali Hassan Mahesar, M. Soomro, M. Magsi, A. A. Baloch, M. Soomro\",\"doi\":\"10.4038/jccpsl.v27i3.8409\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Ischaemic stroke is a heterogeneous multifactorial disorder characterized by acute focal neurological deficit due to cerebrovascular disease. Considering the clinical evidence of dyslipidaemia as a risk factor for ischaemic stroke, there is a need to know the magnitude of dyslipidaemia in patients. Aim of the study was to determine the frequency of dyslipidaemia in patients of ischaemic stroke at a tertiary care teaching hospital in Larkana, Pakistan. Methods: A cross-sectional study was conducted at the Department of Medicine, Shaheed Mohtarma Benazir Bhutto Medical University Hospital Larkana, Pakistan during the period of six months (July-December 2016). All patients between 18-75 years of age of either gender suffering from ischaemic stroke were included. All patients with intracranial haemorrhage, CNS tumour, epilepsy, multiple sclerosis, familial lipid disorders, endocrine disorders, chronic diseases, and on anti-lipid medications, cocaine or alcohol addicts were excluded. The statistical analysis was conducted by using Stata Statistical Software 14. Results: Mean age of enrolled participants was 46.3 (SD=15.2) years. Of 85 enrolled participants, 73 (85.9%) were males and 12 (14.1%) were females, with male to female ratio of 6:1. The frequency of dyslipidaemia was 28 (32.9%), with mean LDL 100.7 (SD=18.4) mg/dl and HDL 42 (SD=11.7) mg/dl and total cholesterol 166.3 (SD=34.3) mg/dl. Conclusions & Recommendations: Dyslipidaemia, with low HDL 13 (15.3%) was found to be the most common risk factor we observed in our patients with stroke. The importance of preventive measures for a disease which has modifiable risk factors (diabetes and hypertension) should be emphasized to reduce the burden of stroke in the country.\",\"PeriodicalId\":120205,\"journal\":{\"name\":\"Journal of the College of Community Physicians of Sri Lanka\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-11-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the College of Community Physicians of Sri Lanka\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4038/jccpsl.v27i3.8409\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the College of Community Physicians of Sri Lanka","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4038/jccpsl.v27i3.8409","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

缺血性脑卒中是一种异质性多因素疾病,以脑血管疾病引起的急性局灶性神经功能缺损为特征。考虑到临床证据表明血脂异常是缺血性卒中的危险因素,有必要了解患者血脂异常的严重程度。该研究的目的是确定巴基斯坦拉卡纳一家三级护理教学医院缺血性卒中患者血脂异常的频率。方法:在巴基斯坦拉卡纳沙希德·莫赫塔玛·贝娜齐尔·布托医科大学医院医学系进行为期6个月(2016年7月- 12月)的横断面研究。所有年龄在18-75岁之间的缺血性卒中患者,不论性别。排除颅内出血、中枢神经系统肿瘤、癫痫、多发性硬化症、家族性脂质紊乱、内分泌紊乱、慢性疾病以及服用抗脂质药物、可卡因或酒精成瘾的患者。采用Stata statistical Software 14进行统计分析。结果:入组参与者的平均年龄为46.3岁(SD=15.2)。85名入组参与者中,男性73人(85.9%),女性12人(14.1%),男女比例为6:1。血脂异常发生率为28例(32.9%),平均LDL为100.7 (SD=18.4) mg/dl, HDL为42 (SD=11.7) mg/dl,总胆固醇为166.3 (SD=34.3) mg/dl。结论与建议:血脂异常伴低HDL - 13(15.3%)是我们观察到的卒中患者中最常见的危险因素。应强调对具有可改变危险因素的疾病(糖尿病和高血压)采取预防措施的重要性,以减轻该国中风的负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dyslipidaemia in ischaemic stroke patients: results from a tertiary care teaching hospital of Pakistan
Introduction: Ischaemic stroke is a heterogeneous multifactorial disorder characterized by acute focal neurological deficit due to cerebrovascular disease. Considering the clinical evidence of dyslipidaemia as a risk factor for ischaemic stroke, there is a need to know the magnitude of dyslipidaemia in patients. Aim of the study was to determine the frequency of dyslipidaemia in patients of ischaemic stroke at a tertiary care teaching hospital in Larkana, Pakistan. Methods: A cross-sectional study was conducted at the Department of Medicine, Shaheed Mohtarma Benazir Bhutto Medical University Hospital Larkana, Pakistan during the period of six months (July-December 2016). All patients between 18-75 years of age of either gender suffering from ischaemic stroke were included. All patients with intracranial haemorrhage, CNS tumour, epilepsy, multiple sclerosis, familial lipid disorders, endocrine disorders, chronic diseases, and on anti-lipid medications, cocaine or alcohol addicts were excluded. The statistical analysis was conducted by using Stata Statistical Software 14. Results: Mean age of enrolled participants was 46.3 (SD=15.2) years. Of 85 enrolled participants, 73 (85.9%) were males and 12 (14.1%) were females, with male to female ratio of 6:1. The frequency of dyslipidaemia was 28 (32.9%), with mean LDL 100.7 (SD=18.4) mg/dl and HDL 42 (SD=11.7) mg/dl and total cholesterol 166.3 (SD=34.3) mg/dl. Conclusions & Recommendations: Dyslipidaemia, with low HDL 13 (15.3%) was found to be the most common risk factor we observed in our patients with stroke. The importance of preventive measures for a disease which has modifiable risk factors (diabetes and hypertension) should be emphasized to reduce the burden of stroke in the country.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信