首个疟疾和贫血综合护理点检测

R. An, Qiaochu Zhang, Zoe Sekyonda, Matthew Lind, Daren Bledsoe, U. Gurkan
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引用次数: 0

摘要

全世界有超过20亿人患有贫血,约占世界人口的25%。贫血有多种原因,包括营养缺乏、原发性血液病和疟疾等传染病。在全世界导致贫血的各种原因中,疟疾是撒哈拉以南非洲第三大流行原因,全球第八大流行原因。由于缺乏实验室基础设施和熟练人员以及财政资源不足,贫血和疟疾的诊断/监测在低收入和中等收入国家具有挑战性。我们扩展了之前建立的Gazelle™疟疾检测系统,增加了总血红蛋白定量和贫血检测能力。新型Gazelle贫血-疟疾(Gazelle- a&m)可低成本批量生产,并提供首个也是唯一的单点护理(POC)检测,用于便携、负担得起且准确的贫血和疟疾诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
First Integrated Point-of-Care Test for Malaria and Anemia
Anemia affects more than 2 billion people worldwide, which is about 25% of the world’s population. Anemia has numerous causes ranging from nutritional deficiencies, primary hematologic diseases, and infectious diseases such as malaria. Among the various causes of anemia world-wide, malaria is the 3rd most prevalent cause in Sub-Saharan Africa and the 8th most prevalent cause globally. Anemia and malaria diagnosis/monitoring are challenging in low- and middle-income countries due to lack of laboratory infrastructure and skilled personnel as well as insufficient financial resources. We extended our previously established Gazelle™ malaria detection system to add total hemoglobin quantification and anemia testing capability. The new Gazelle Anemia-Malaria (Gazelle-A&M) is mass-producible at low cost and offers the first and only single point-of-care (POC) test for portable, affordable, and accurate, anemia and malaria diagnosis.
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