结合ConvLSTM和注意机制诊断ADHD的脑电图信号

M. Bakhtyari, S. Mirzaei, H. Amiri
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引用次数: 1

摘要

在神经发育障碍中,注意缺陷多动障碍(ADHD)是儿童时期最常见的疾病。早期诊断和治疗这种疾病可以减少负面影响,如学习困难、反社会行为、经济问题和成年后离婚。虽然目前有临床诊断,但它们是基于患者的行为,并不可靠。研究人员开发了不同的方法来发现一种有助于准确诊断的生物标志物。生物信号如脑电图(EEG)由于能够记录神经元的电活动而引起了人们最大的兴趣。我们提出了一个结合ConvLSTM和注意机制的深度学习框架。为了提供这个框架的输入,我们首先计算一个动态连接张量。该方法比基于傅里叶变换和非线性分析的特征提取方法更有效。由于ConvLSTM的结构,该模型可以同时提取时间和空间特征,并且注意机制为模型对脑电数据的不同时间瞬间进行评分提供了思路。这两个步骤导致有效地编码一个紧凑的脑电图信号表示。首次将ConvLSTM与注意机制相结合应用于时间序列数据。为了检验提议的框架,我们在400个数据实例上运行实验。我们使用5倍交叉验证来训练我们的模型。经过10次不同的执行,最佳模型的准确率达到99.75%,是在该数据的研究中表现最好的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Combination of ConvLSTM and Attention mechanism to diagnose ADHD based on EEG signals
Among neurodevelopmental disorders, attention deficit hyperactivity disorder (ADHD) is the most prevalent disorder in childhood. Early diagnosis and treatment of this disorder can reduce negative impacts, such as learning difficulty, antisocial behaviours, financial problems and divorce in adulthood. Although clinical diagnoses are currently available, they are based on patient behaviours and are not reliable. Researchers developed different methods to discover a biomarker that can help accurate diagnosis. Biological signals such as electroencephalography (EEG) draw the most interest because of their ability to record neurons electrical activity. We propose a deep learning framework that combines the ConvLSTM and attention mechanism. To provide the input for this framework, we first calculate a dynamic connectivity tensor. This technique is more effective than feature extraction methods such as Fourier transform-based approaches and nonlinear analyses. Due to the structure of ConvLSTM, the model can extract temporal and spatial features simultaneously, and the attention mechanism provides insights for the model to score different time instants in EEG data. These two steps lead to effectively encoding a compact representation of EEG signals. It is the first time to apply ConvLSTM and the attention mechanism combination on time series data. To examine the proposed framework, we run our experiments on 400 data instances. We trained our model using 5-fold cross-validation. After ten different executions, the best model has an accuracy of 99.75%, which is the superior performance among the studies on this data.
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