确定接种疫苗后个体COVID-19感染率及其严重程度

Azmat Ali, Abdur Rahman Butt
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摘要

目的:评估接种人群Covid-19感染的发生率,并对疾病严重程度进行分类。方法:本横断面研究于2021年9月至2022年2月在伊斯兰堡KRL医院医学部进行。18岁以上、完全接种疫苗的个体被纳入研究。采用预先验证的基于访谈的封闭式问卷收集数据,获得知情同意,并使用SPSS Statistics 23对数据进行分析。根据世卫组织的严重程度定义确定COVID-19的严重程度。结果:该研究包括362人。男性55.00%,女性45.00%。年龄最小20岁,最大76岁,平均45.73±14.919岁。27.1%的参与者有合并症,其中糖尿病最为常见(59.18%)。大多数(37.84%)接种了国药疫苗。其次是辉瑞(24.58%)和Moderna(13.82%)。158例(43.65%)报告感染新冠肺炎。158例患者中,41例(25.94%)为重症感染,9例(5.70%)为危重感染。结论:充分接种疫苗者感染新冠病毒的比例相当大(43.64%)。辉瑞疫苗预防感染最有效(79.77%)。而国药集团疗效最低(41.60%)。然而,大量患者(86.18%)接种疫苗可有效预防重症和危重型感染。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Determining the Rate of COVID-19 Infection in Post-Vaccinated Individuals and Its Severity
Objective: To assess the incidence of Covid-19 infection in people who were vaccinated and to categorize disease severity. Methodology: This cross sectional study was carried out at the Department of Medicine, KRL Hospital, Islamabad from September 2021 to February 2022. Individuals above 18 years of age, and fully vaccinated were included in the study. Using a pre-validated interview based close ended questionnaire data was collected, informed consent was obtained, and data was analyzed using SPSS Statistics 23. The severity of COVID-19 was determined by applying the WHO severity definitions. Results: The study included 362 individuals. 55.00% were males and 45.00% were females. The minimum age was 20 years and maximum 76 years with a mean of 45.73 ± 14.919. 27.1% of the participants had co morbidities, of which diabetes was the most frequent (59.18%). Majority (37.84%) individuals received Sinopharm vaccine. This was followed by Pfizer (24.58%) and Moderna (13.82%). 158 patients (43.65%) reported infection with covid-19. Out of 158, 41 (25.94%) had severe infection and 9 (5.70%) had critical infection on WHO criteria. Conclusion: A substantial proportion of fully vaccinated individuals suffered from Covid-19 infection (43.64%). Pfizer was the most effective vaccine in preventing infection (79.77%). While Sinopharm was the least effective (41.60%). However, vaccination was effective in preventing severe and critical infection in a significant number of patients (86.18%).
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