Computational Cardiovascular Medicine With Isogeometric Analysis

Isogeometric analysis (IGA) brought superior accuracy to computations in both fluid and solid mechanics. The increased accuracy has been in representing both the problem geometry and the variables computed. Beyond using IGA basis functions in space, with IGA basis functions in time in a space–time (ST) context, we can have increased accuracy also in representing the motion of solid surfaces. Around the core methods such as the residual-based variational multiscale (VMS), ST-VMS and arbitrary Lagrangian–Eulerian VMS methods, with complex-geometry IGA mesh generation methods and immersogeometric analysis, and with special methods targeting specific classes of computations, the IGA has been very effective in computational cardiovascular medicine. We provide an overview of these IGA-based computational cardiovascular-medicine methods and present examples of the computations performed.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.