双层材料介电光谱的双同轴探针方法在生物学上的应用

Masahito Nakamura, T. Tajima, M. Seyama
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引用次数: 0

摘要

本文提出了一种新的开放式同轴探头导纳建模的测量方法,该方法测量两层材料,而不依赖于内层介电光谱的第一层厚度。同轴探头的穿透深度取决于探头孔径,这导致层状材料测量的有效介电常数存在差异。因此,我们的解析导纳模型使用两个不同穿透深度的同轴探针,并使用两个探针测量的有效介电常数来计算导纳。我们通过体外测量来评估模型的准确性,假设生物医学样本如人类皮肤。结果表明,在0.5 ~ 10ghz频率范围内,测得的导纳与实验结果吻合较好。虽然计算中没有考虑第一层的厚度,但与测量导纳的误差在10%以内。由于生物材料由两层结构组成以保持水分,因此所提出的方法有望用于新型生物传感应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Two-Coaxial-Probe Method for Dielectric Spectroscopy of Two-Layer Materials Towards Biological Application
This paper proposes a novel measurement method for admittance modelling of open-ended coaxial probes that measure two-layer material independently of the thickness of the first layer for dielectric spectroscopy of the inner layer. The penetration depth of a coaxial probe depends on the probe aperture, which results in differences in the measured effective dielectric constant for layered materials. Therefore, our analytical admittance model uses two coaxial probes with different penetration depths, and we calculate the admittance using the effective dielectric constant measured by both probes. We evaluated the accuracy of the model by in vitro measurement, assuming biomedical samples such as human skin. The results show good agreement with measured admittance in the frequency range from 0.5 to 10 GHz. The error with the measured admittance was within 10%, though the thickness of the first layer was not included in the calculation. Since biological materials are composed of a two-layer structure to retain moisture, the proposed method is expected to be used for novel biological sensing applications.
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