{"title":"破坏和抑制口腔生物膜形成的当前策略","authors":"Quratul Ann Hussain","doi":"10.32474/IPDOAJ.2021.05.000217","DOIUrl":null,"url":null,"abstract":"Oral biofilm, an organized community comprises of extensive\nvariety of microbes rooted with extracellular polysaccharides\n(EPS) matrix. It is recognized as a virulence factor to numerous oral\ninfectious diseases including dental caries, gingivitis, periodontitis,\nperiapical periodontitis and peri-implantitis [1]. Biofilm formation\non medical devices such as mechanical heart valves, catheters,\ncontact lenses and prosthetic joints pose a critical medical problem.\nBoth gram positive and negative bacteria can form biofilms on\nmedical devices. Medical device infections are accountable for\nalmost 60% of hospital acquired infections. In the United States,\nthe anticipated expense of caring for healthcare-associated\ninfections is nearly between $28 billion and $45 billion each year\n[2]. The lifecycle of a conventional biofilm comprises of bacterial\nattachment, biofilm growth/maturation, and biofilm dispersion.","PeriodicalId":106996,"journal":{"name":"Interventions in Pediatric Dentistry Open Access Journal","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Current Strategies for The Disruption and Inhibition of Oral Biofilm Formation\",\"authors\":\"Quratul Ann Hussain\",\"doi\":\"10.32474/IPDOAJ.2021.05.000217\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Oral biofilm, an organized community comprises of extensive\\nvariety of microbes rooted with extracellular polysaccharides\\n(EPS) matrix. It is recognized as a virulence factor to numerous oral\\ninfectious diseases including dental caries, gingivitis, periodontitis,\\nperiapical periodontitis and peri-implantitis [1]. Biofilm formation\\non medical devices such as mechanical heart valves, catheters,\\ncontact lenses and prosthetic joints pose a critical medical problem.\\nBoth gram positive and negative bacteria can form biofilms on\\nmedical devices. Medical device infections are accountable for\\nalmost 60% of hospital acquired infections. In the United States,\\nthe anticipated expense of caring for healthcare-associated\\ninfections is nearly between $28 billion and $45 billion each year\\n[2]. The lifecycle of a conventional biofilm comprises of bacterial\\nattachment, biofilm growth/maturation, and biofilm dispersion.\",\"PeriodicalId\":106996,\"journal\":{\"name\":\"Interventions in Pediatric Dentistry Open Access Journal\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Interventions in Pediatric Dentistry Open Access Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32474/IPDOAJ.2021.05.000217\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Interventions in Pediatric Dentistry Open Access Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32474/IPDOAJ.2021.05.000217","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Current Strategies for The Disruption and Inhibition of Oral Biofilm Formation
Oral biofilm, an organized community comprises of extensive
variety of microbes rooted with extracellular polysaccharides
(EPS) matrix. It is recognized as a virulence factor to numerous oral
infectious diseases including dental caries, gingivitis, periodontitis,
periapical periodontitis and peri-implantitis [1]. Biofilm formation
on medical devices such as mechanical heart valves, catheters,
contact lenses and prosthetic joints pose a critical medical problem.
Both gram positive and negative bacteria can form biofilms on
medical devices. Medical device infections are accountable for
almost 60% of hospital acquired infections. In the United States,
the anticipated expense of caring for healthcare-associated
infections is nearly between $28 billion and $45 billion each year
[2]. The lifecycle of a conventional biofilm comprises of bacterial
attachment, biofilm growth/maturation, and biofilm dispersion.