{"title":"挽救性全喉切除术后的生存率:既往治疗的影响","authors":"I. Stanković, D. Milisavljevic, M. Stankovic","doi":"10.4172/2155-9619.1000322","DOIUrl":null,"url":null,"abstract":"Purpose: To compare the complications and survival rate after different treatment modalities of advanced \nlaryngopharyngeal cancer. \nMethods: Retrospective study included 619 advanced laryngopharyngeal carcinoma, treated with either primary \n total laryngectomy (PTL), or salvage (STL) after partial laryngectomy, radio, chemoradiotherapy. Complications and \nsurvival rate were documented. \nResults: Five years disease free survival rate amounted 60.9% for PTL, 54.3% for STL after partial \n laryngectomy, 50% for STL after radiotherapy and 43.8% for STL after chemoradiotherapy. Histologically positive \nneck was highly significantly associated with worse prognosis, much more than recurrence within larynx. \nConclusion: PTL gives the best survival rate with low complications for advanced laryngopharyngeal squamous \n cell carcinoma. Complications and survival rate of STL significantly depend on previous treatment of \nlaryngopharyngeal cancer.","PeriodicalId":302578,"journal":{"name":"Journal of Nuclear Medicine and Radiation Therapy","volume":"3 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2017-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Survival after Salvage Total Laryngectomy: The Influence of Previous Treatment\",\"authors\":\"I. Stanković, D. Milisavljevic, M. Stankovic\",\"doi\":\"10.4172/2155-9619.1000322\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Purpose: To compare the complications and survival rate after different treatment modalities of advanced \\nlaryngopharyngeal cancer. \\nMethods: Retrospective study included 619 advanced laryngopharyngeal carcinoma, treated with either primary \\n total laryngectomy (PTL), or salvage (STL) after partial laryngectomy, radio, chemoradiotherapy. Complications and \\nsurvival rate were documented. \\nResults: Five years disease free survival rate amounted 60.9% for PTL, 54.3% for STL after partial \\n laryngectomy, 50% for STL after radiotherapy and 43.8% for STL after chemoradiotherapy. Histologically positive \\nneck was highly significantly associated with worse prognosis, much more than recurrence within larynx. \\nConclusion: PTL gives the best survival rate with low complications for advanced laryngopharyngeal squamous \\n cell carcinoma. Complications and survival rate of STL significantly depend on previous treatment of \\nlaryngopharyngeal cancer.\",\"PeriodicalId\":302578,\"journal\":{\"name\":\"Journal of Nuclear Medicine and Radiation Therapy\",\"volume\":\"3 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-01-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Nuclear Medicine and Radiation Therapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4172/2155-9619.1000322\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Nuclear Medicine and Radiation Therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2155-9619.1000322","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Survival after Salvage Total Laryngectomy: The Influence of Previous Treatment
Purpose: To compare the complications and survival rate after different treatment modalities of advanced
laryngopharyngeal cancer.
Methods: Retrospective study included 619 advanced laryngopharyngeal carcinoma, treated with either primary
total laryngectomy (PTL), or salvage (STL) after partial laryngectomy, radio, chemoradiotherapy. Complications and
survival rate were documented.
Results: Five years disease free survival rate amounted 60.9% for PTL, 54.3% for STL after partial
laryngectomy, 50% for STL after radiotherapy and 43.8% for STL after chemoradiotherapy. Histologically positive
neck was highly significantly associated with worse prognosis, much more than recurrence within larynx.
Conclusion: PTL gives the best survival rate with low complications for advanced laryngopharyngeal squamous
cell carcinoma. Complications and survival rate of STL significantly depend on previous treatment of
laryngopharyngeal cancer.
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