尽管产前保健取得进展,但产妇死亡不可预防;一份病例报告

J. Warushahennadi
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摘要

主动脉夹层(AoD)是一种非常罕见但潜在致命的妊娠疾病。妊娠期急性主动脉夹层的发生率约为每10万人中每年0.4例。一名28岁38周的初级产妇在从心脏病专家例行访问返回时突然出现烧灼性胃痛,随后被转介到医院。她在病房接受胃炎治疗,几小时后出现呼吸短促、胸闷痛和心动过速。尽管采取了包括6单位输血在内的强化复苏措施,但在拔管后不久,她还是出现了心脏骤停。她在怀孕前被诊断为轻度主动脉瓣反流和轻微二尖瓣反流,并在妊娠早期被转诊到心脏病专家,并被确认为低心脏病风险。在所有三个月期间,她都被心脏病专家看到,并被认为是低心脏病风险。尸检结果显示,胸腔内有2750毫升血,腹腔内有750毫升血。有一堆血渗进了主动脉周围的纵隔组织。肉眼可见主动脉夹层,镜下可见中膜变性,内膜呈穿透性撕裂,并有血液渗漏至周围组织。本病例报告表明,妊娠本身是AoD发展的一个危险因素,AoD导致妊娠期间的灾难性障碍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Unpreventable Maternal Death In Spite Of the Advances in Antenatal Care; a Case Report
Aortic dissection (AoD) is a very rare but potentially fatal entity during pregnancy. The incidence of acute aortic dissection during pregnancy is about 0.4 cases per 100 000 persons yearly. A 28-year-old 38-week primi was referred to the hospital following sudden onset of burning epigastric pain which developed while returning from the routine visit to the cardiologist. She was treated for gastritis in the ward and a few hours later she developed shortness of breath, tight chest pain and tachycardia. Emergency LSCS was done and a live baby was delivered and she had sudden cardiac arrest soon after the extubation, in spite of the intensive resuscitation measures including six units of blood transfusion. She was diagnosed with mild aortic regurgitation and trivial mitral regurgitation before the pregnancy and was referred to the cardiologist during the first trimester and was confirmed with low cardiac risk.  She was seen by the cardiologist during all 3 trimesters and was concluded with low cardiac risk. The autopsy revealed 2750 ml of blood in the chest cavity and 750 ml of blood in the abdominal cavity. There was a collection of blood which was infiltrated into the mediastinal tissues around the aorta. There were macroscopic features of aortic dissection and the microscopy of the aorta revealed degeneration of tunica media, a through and through tear on intima with leakage of blood into the surrounding tissues.  This case report illustrates that the pregnancy itself is a risk factor for the development of AoD which leads to the catastrophic disorder in pregnancy.
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