Hugo Girão, Naoyuki Okada, T. Rodrigues, Alexandra Silva, A. C. Figueiredo, Z. García, Tatiana Moutinho‐Santos, I. Hayashi, Jorge E Azevedo, Sandra Macedo-Ribeiro, H. Maiato
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CLASP2 binding to curved microtubule tips promotes flux and stabilizes kinetochore attachments
Girão et al. use structure-guided functional mutants of CLASP2 to show that recognition of growing microtubule plus-ends through EB–protein interaction and the ability to associate with curved microtubule protofilaments through TOG2 and TOG3 domains promote growth and stabilization of kinetochore–microtubules required for poleward flux.
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