生物杂交视网膜植入物:2005年研究进展

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI:10.1109/CNE.2005.1419603

Tohru Yagi, M. Watanabe, Yasushi Ohnishi, Shigeru Okuma, Toshiharu Mukai

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引用次数: 10

摘要

自90年代中期以来，我们的研究小组一直在开发一种生物混合视网膜植入物，这是一种结合微机电系统(MEMS)技术和再生医学的视觉假体。在这种植入中，附着在MEMS上的神经轴突通过周围神经移植物引导到中枢神经系统(CNS)。由于神经元在MEMS和CNS之间形成功能性连接，电刺激使生物杂交视网膜植入物中的神经元向CNS发送视觉信息。我们最近的研究包括生物mems的第一个原型，各种微/纳米电极阵列的开发，体外神经细胞培养和轴突引导实验，在体内电刺激实验，以及各种计算机模拟，包括使用视觉假体模拟器进行阅读能力的心理物理评估

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Biohybrid Retinal Implant: Research and Development Update in 2005

Since the mid-90's, our research group has been developing a biohybrid retinal implant, which is a visual prosthesis that combines microelectromechanical system (MEMS) technology and regenerative medicine. In this implant, the neural axons attached on the MEMS are guided toward the central nervous system (CNS) by a peripheral nerve graft. Because neurons form functional connections between the MEMS and the CNS, electrical stimulation causes the neurons in the biohybrid retinal implant to send visual information to the CNS. Our recent research has included the first prototype of bio-MEMS, the development of various micro/nanoelectrode arrays, in vitro nerve cell culture and axon guidance experiments on the fabricated electrode array, in vivo electrical stimulation experiments, and various computer simulations including the psychophysical evaluation of reading ability with a visual prosthesis simulator

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Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005.

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