J.A. Herrera-Muñoz, J. Gómez-Sánchez, D.A. Preciado-Estrella, J. Sedano-Basilio, L. Trujillo-Ortiz, I. Uberetagoyena-Tello de Meneses, A. Palmeros-Rodríguez, V. Cornejo-Dávila, G. Fernández-Noyola, M. Cantellano-Orozco, C. Martínez-Arroyo, J.G. Morales-Montor, C. Pacheco-Gahbler
{"title":"经尿道前列腺切除术后药物使用及手术再治疗的发生率及相关因素","authors":"J.A. Herrera-Muñoz, J. Gómez-Sánchez, D.A. Preciado-Estrella, J. Sedano-Basilio, L. Trujillo-Ortiz, I. Uberetagoyena-Tello de Meneses, A. Palmeros-Rodríguez, V. Cornejo-Dávila, G. Fernández-Noyola, M. Cantellano-Orozco, C. Martínez-Arroyo, J.G. Morales-Montor, C. Pacheco-Gahbler","doi":"10.1016/j.uromx.2016.02.004","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Transurethral resection of the prostate (TURP) is a standard procedure for obstructive prostatic growth. Medical retreatment with anticholinergics, alpha-blockers, and 5 alpha reductase inhibitors is from 16 to 50%. A second surgical retreatment is associated with internal urethrotomy, cervicotomy, and re-TURP between 5 and 13% at 5 years. Re-TURP is associated with residual tissue.</p></div><div><h3>Aim</h3><p>To determine the incidence of and factors associated with the use of medications and surgical retreatment after TURP.</p></div><div><h3>Material and methods</h3><p>A retrospective study was conducted on patients that underwent TURP within the time frame of January 2010 and December 2011 with follow-up to the present. Preoperative, intraoperative, and postoperative variables were analyzed and the chi-square test was used for the statistical analysis.</p></div><div><h3>Results</h3><p>Follow-up was carried out on 158 patients that underwent TURP. The overall accumulated incidence of retreatment was 43%, surgical retreatment was 17.7%, and medical treatment was 30.4%. TURP retreatment was 7.6% and transvesical prostatectomy was 1.3%. The mean time until prostate surgery retreatment was 30.5 months. Postoperative medical treatment was: anticholinergics 17.1%, alpha-blockers 15.2%, 5 alpha reductase inhibitors 6.3%, and combination 8.2%. During follow-up, 22.8% of the patients had residual tissue, which was the main cause of retreatment. Preoperative prostatic volume<!--> <!-->><!--> <!-->80<!--> <!-->g was associated with residual tissue (p<!--> <!-->=<!--> <!-->0.024).</p></div><div><h3>Conclusions</h3><p>In our study, the incidence of surgical retreatment was higher than that reported in the literature, at 17.7% vs. 13%, respectively, and medical treatment was lower at 30.4% vs. 50%, respectively. Anticholinergics were the most utilized medications. Adequate patient selection will reduce complications and risk for retreatment.</p></div>","PeriodicalId":34909,"journal":{"name":"Revista mexicana de urologia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.uromx.2016.02.004","citationCount":"0","resultStr":"{\"title\":\"Incidencia y factores asociados al uso de medicamentos y retratamiento quirúrgico posterior a resección transuretral de próstata\",\"authors\":\"J.A. Herrera-Muñoz, J. Gómez-Sánchez, D.A. Preciado-Estrella, J. Sedano-Basilio, L. Trujillo-Ortiz, I. Uberetagoyena-Tello de Meneses, A. Palmeros-Rodríguez, V. Cornejo-Dávila, G. Fernández-Noyola, M. Cantellano-Orozco, C. Martínez-Arroyo, J.G. Morales-Montor, C. Pacheco-Gahbler\",\"doi\":\"10.1016/j.uromx.2016.02.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p>Transurethral resection of the prostate (TURP) is a standard procedure for obstructive prostatic growth. Medical retreatment with anticholinergics, alpha-blockers, and 5 alpha reductase inhibitors is from 16 to 50%. A second surgical retreatment is associated with internal urethrotomy, cervicotomy, and re-TURP between 5 and 13% at 5 years. Re-TURP is associated with residual tissue.</p></div><div><h3>Aim</h3><p>To determine the incidence of and factors associated with the use of medications and surgical retreatment after TURP.</p></div><div><h3>Material and methods</h3><p>A retrospective study was conducted on patients that underwent TURP within the time frame of January 2010 and December 2011 with follow-up to the present. Preoperative, intraoperative, and postoperative variables were analyzed and the chi-square test was used for the statistical analysis.</p></div><div><h3>Results</h3><p>Follow-up was carried out on 158 patients that underwent TURP. The overall accumulated incidence of retreatment was 43%, surgical retreatment was 17.7%, and medical treatment was 30.4%. TURP retreatment was 7.6% and transvesical prostatectomy was 1.3%. The mean time until prostate surgery retreatment was 30.5 months. Postoperative medical treatment was: anticholinergics 17.1%, alpha-blockers 15.2%, 5 alpha reductase inhibitors 6.3%, and combination 8.2%. During follow-up, 22.8% of the patients had residual tissue, which was the main cause of retreatment. Preoperative prostatic volume<!--> <!-->><!--> <!-->80<!--> <!-->g was associated with residual tissue (p<!--> <!-->=<!--> <!-->0.024).</p></div><div><h3>Conclusions</h3><p>In our study, the incidence of surgical retreatment was higher than that reported in the literature, at 17.7% vs. 13%, respectively, and medical treatment was lower at 30.4% vs. 50%, respectively. Anticholinergics were the most utilized medications. Adequate patient selection will reduce complications and risk for retreatment.</p></div>\",\"PeriodicalId\":34909,\"journal\":{\"name\":\"Revista mexicana de urologia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.uromx.2016.02.004\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista mexicana de urologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2007408516000264\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista mexicana de urologia","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2007408516000264","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Incidencia y factores asociados al uso de medicamentos y retratamiento quirúrgico posterior a resección transuretral de próstata
Introduction
Transurethral resection of the prostate (TURP) is a standard procedure for obstructive prostatic growth. Medical retreatment with anticholinergics, alpha-blockers, and 5 alpha reductase inhibitors is from 16 to 50%. A second surgical retreatment is associated with internal urethrotomy, cervicotomy, and re-TURP between 5 and 13% at 5 years. Re-TURP is associated with residual tissue.
Aim
To determine the incidence of and factors associated with the use of medications and surgical retreatment after TURP.
Material and methods
A retrospective study was conducted on patients that underwent TURP within the time frame of January 2010 and December 2011 with follow-up to the present. Preoperative, intraoperative, and postoperative variables were analyzed and the chi-square test was used for the statistical analysis.
Results
Follow-up was carried out on 158 patients that underwent TURP. The overall accumulated incidence of retreatment was 43%, surgical retreatment was 17.7%, and medical treatment was 30.4%. TURP retreatment was 7.6% and transvesical prostatectomy was 1.3%. The mean time until prostate surgery retreatment was 30.5 months. Postoperative medical treatment was: anticholinergics 17.1%, alpha-blockers 15.2%, 5 alpha reductase inhibitors 6.3%, and combination 8.2%. During follow-up, 22.8% of the patients had residual tissue, which was the main cause of retreatment. Preoperative prostatic volume > 80 g was associated with residual tissue (p = 0.024).
Conclusions
In our study, the incidence of surgical retreatment was higher than that reported in the literature, at 17.7% vs. 13%, respectively, and medical treatment was lower at 30.4% vs. 50%, respectively. Anticholinergics were the most utilized medications. Adequate patient selection will reduce complications and risk for retreatment.
期刊介绍:
Revista Mexicana de Urología (RMU) [Mexican Journal of Urology] (ISSN: 0185-4542 / ISSN electronic: 2007-4085) is bimonthly publication that disseminates research by academicians and professionals of the international medical community interested in urological subjects, in the format of original articles, clinical cases, review articles brief communications and letters to the editor. Owing to its nature, it is publication with international scope that disseminates contributions in Spanish and English that are rigorously reviewed by peers under the double blind modality. Neither journalistic documents nor those that lack rigorous medical or scientific support are suitable for publication.