Explore of Hyperbaric Oxygen Therapy on the Patients with Acute Encephalopathy Scondery Myocardial Damage Following Carbon Monoxide Poising

Objective: To investigate the myocardial damage and hyperbaric oxygen treatment of acute encephalopathy in CO poisoning. Methods: Since March 2015 - March 2020 admitted to 125 patients with acute CO poisoning encephalopathy, emergency admission GCS score 7-8 points or less, and the intracranial pressure, myocardial damage markers enzymes (CK - MB, CK, LDH, MYO, BNP) and troponin (cTnl), arterial COHb quantitative and electrocardiogram (EKG) dynamic inspection, row CT, MRI examination can at the same time, using air pressure cabin HBO treatment, Each patient choose 2.5-3 period of treatment (Every10 times is a course of treatment), 99.5-100% oxygen purity (liquid oxygen gasification), oxygen supply time 60 minutes or 80 minutes, interlude 10 minutes. Results: The higher the COHb, the deeper the coma, the increased intracranial pressure, the intracranial hypertension, and the morphological changes such as diffuse cerebral edema and symmetrical globulin necrosis were observed in 125 patients. However, the myocardial damaging enzymes and troponin markers were significantly increased and the EKG abnormalities were basically consistent. HBO treatment achieved remarkable curative effect, the incidence of delayed encephalopathy was significantly reduced, and no death occurred. Conclusion: Increased intracranial pressure induced by acute encephalopathy induced by CO poisoning can significantly increase the incidence of myocardial damage, subendocardial myocardial infarction, left heart failure and various arrhythmias. HBO is a treatment for etiology and should be preferred.