{"title":"芯片上太赫兹分析生物分子的设计考虑","authors":"T. Baras, T. Kleine-Ostmann, M. Koch","doi":"10.1109/THZ.2002.1037594","DOIUrl":null,"url":null,"abstract":"Recently the marker free distinction between different kinds of biomolecules, e.g. hybridised (double-stranded) DNA (HDNA) and denatured (single-stranded) DNA (DDNA) using THz time-domain on-chip analysis has been demonstrated. Here we numerically examine the influence of critical experimental parameters on the transmission characteristics of a variety of microstrip resonators loaded with test samples of different thickness and refractive index.","PeriodicalId":143116,"journal":{"name":"Proceedings, IEEE Tenth International Conference on Terahertz Electronics","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2002-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Design considerations for on-chip THz analysis of biomolecules\",\"authors\":\"T. Baras, T. Kleine-Ostmann, M. Koch\",\"doi\":\"10.1109/THZ.2002.1037594\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Recently the marker free distinction between different kinds of biomolecules, e.g. hybridised (double-stranded) DNA (HDNA) and denatured (single-stranded) DNA (DDNA) using THz time-domain on-chip analysis has been demonstrated. Here we numerically examine the influence of critical experimental parameters on the transmission characteristics of a variety of microstrip resonators loaded with test samples of different thickness and refractive index.\",\"PeriodicalId\":143116,\"journal\":{\"name\":\"Proceedings, IEEE Tenth International Conference on Terahertz Electronics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2002-11-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings, IEEE Tenth International Conference on Terahertz Electronics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/THZ.2002.1037594\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings, IEEE Tenth International Conference on Terahertz Electronics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/THZ.2002.1037594","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Design considerations for on-chip THz analysis of biomolecules
Recently the marker free distinction between different kinds of biomolecules, e.g. hybridised (double-stranded) DNA (HDNA) and denatured (single-stranded) DNA (DDNA) using THz time-domain on-chip analysis has been demonstrated. Here we numerically examine the influence of critical experimental parameters on the transmission characteristics of a variety of microstrip resonators loaded with test samples of different thickness and refractive index.
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