流行病学逆问题的数值模拟

Zh. M. Bektemessov, S. Kabanikhin, S. Kasenov
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摘要

本文研究了COVID-19冠状病毒传播的数学隔间模型。这篇文章由六段组成。在这项研究中,从跨学科的角度研究流行病暴发,使用易感-感染-康复-死亡(SEIRD)模型的扩展,该模型是基于研究人群群体平均行为的数学室模型。许多传染病的特点是从接触到出现临床症状之间有一段潜伏期。与有临床症状的受试者相比,暴露于感染的受试者对公众的危险要大得多。研究一类非线性SEIRD微分方程组。对于直接问题的数值解,考虑了四阶龙格-库塔方法。在建模中,关系是基于主题领域的规律派生的,并允许您根据其参数确定工作框架中变化的性质。提出了确定该系统系数的逆问题。利用遗传算法求解了反问题。介绍了遗传算法的实现方法。得到了数值结果,并与准确数据进行了对比分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ON NUMERICAL MODELING OF THE INVERSE EPIDEMIOLOGY PROBLEM
The article examines a mathematical compartment model of the spread of the COVID-19 coronavirus. The article consists of six paragraphs. In this study, epidemic outbreaks are studied from an interdisciplinary point of view using an extension of the susceptible-infected-recovered-deceased (SEIRD) model, which is a mathematical chamber model based on the average behavior of the studied population group. Many infectious diseases are characterized by an incubation period between exposure and the appearance of clinical symptoms. Subjects exposed to infection are much more dangerous to the public compared to subjects who have clinical symptoms. A nonlinear system of SEIRD differential equations is considered. For the numerical solution of a direct problem, the fourth-order Runge-Kutta method is considered. In modeling, the relationship is derived based on the laws of the subject area and allows you to determine the nature of changes in the framework of the work, depending on its parameters. The inverse problem is posed to determine the coefficients of this system. The inverse problem was solved by the method of a genetic algorithm. The method of the genetic algorithm is described. Numerical results are obtained and a comparative analysis with accurate data is made.
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