膝神经射频根治术治疗膝骨关节炎慢性疼痛的疗效观察

Dr. Shahzad Anwar, Dr. Muhammad Waseem Hassan, Dr. Syed Shahabud Din, Dr. Shoaib Ahmed, Fatima Tirmzi
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摘要

背景:骨关节炎(OA)是老年人下肢残疾最常见的原因,主要影响下肢关节,如膝关节和髋关节。有合并症的老年患者可能不适合手术。对于这些难以治疗的病例,射频根治术可能是一种有效的替代治疗方法。同样,研究发现射频治疗可以通过防止疼痛信号的传递来改善关节功能和减轻疼痛,从而缓解患者的疼痛。目的:评价膝神经射频根治术治疗膝骨关节炎所致膝关节疼痛的疗效。结果:本研究共纳入100例患者。患者平均年龄62.7+9.7岁。大多数患者为女性(69%)、已婚(79%)和超重(58.0%)。至于受影响的膝关节部位,分别有39%的患者是左膝,34%的患者是右膝,29%的患者是双膝。治疗前后随访患者平均评分差异有统计学意义。治疗前第1周平均疼痛评分为7.63+1.11。随访平均疼痛评分为3.94+0.874,第12周进一步降低至1.51+1.12。从基线到随访第12周,疼痛评分、OKS和HADs均有显著改善,表明RFA是治疗OA膝痛的有效方法(p值<0.05),膝神经射频根治术是治疗OA膝痛的有效方法(p值<0.05)。结论:膝神经射频根治术是治疗膝关节炎慢性疼痛的一种安全有效的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effectiveness of radiofrequency rhizotomies of genicular nerves for treating chronic pain in knee osteoarthritis
Background: Osteoarthritis (OA) is the most common cause of lower extremity disability in the elderly, primarily affecting lower extremity joints, such as the knee and hip. Elder patients with comorbidities may not be suitable candidates for surgery. For these difficult to treat cases, radiofrequency (RF) rhizotomies may be an effective alternative treatment. Likewise, it has been found that RF therapy can improve joint function and reduce pain by preventing the transmission of pain signals thus easing the patient. Objective: To evaluate the effectiveness of radiofrequency rhizotomies of genicular nerves in treating knee pain caused by knee osteoarthritis. Results: A total of 100 patients were enrolled in the current study. The mean age of patients was 62.7+9.7. Majority of the patients were female (69%), married (79%), and overweight (58.0%). Regarding affected knee sites, 39% had left, 34% right and 29% had both knees affected, respectively. There was a significant difference in mean scores among patients before and after treatment follow-up. The mean pain score before starting the treatment was 7.63+1.11, in the 1st week. The follow up mean pain score was 3.94+0.874, which further reduced in the 12th week to 1.51+1.12. The pain score, OKS and HADs significantly improved from baseline to 12th week follow up which shows that RFA was an effective treatment for OA knee pain (P-value <0.05) which shows that Radiofrequency rhizotomies of genicular nerves was an effective treatment for OA knee pain (P-value <0.05). Conclusion: Radiofrequency rhizotomies of genicular nerves is a safe and effective treatment option for patients suffering from chronic pain caused by knee OA.
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