A Polubiec, Z Krasnopolska-Polanczky, W Duda-Król, I Jórasz, J Witkowski
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Evaluation of the antiemetic effect of domperidon in patients treated with cytostatic drugs.
Forty patients with various neoplastic syndromes received domperidon as a drug reducing nausea and vomiting. The drug prevents in the daily dose of 30 mg completely the occurrence of nausea and vomiting in 30% of the patients and in 58% considerably reduces their intensity. The dose of 60 mg abolishes nausea and vomiting in 60% of the patients and alleviates in 35%. The drug had been administered through the whole period of chemotherapy without any side effects which may be attributed to its antagonist action to dopamine.
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