预测慢性阻塞性肺疾病的混合特征选择模型

Uppuluri Ruchitha Venkata Sai Meenakshi, V. Jindal
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摘要

慢性阻塞性肺疾病(COPD)的特点是慢性气流受限,通常是进行性的,并且气道中的有害颗粒或气体引发的慢性炎症反应增加。一般情况下,症状、病史、临床检查和肺通气梗阻对诊断起着至关重要的作用。然而,慢性阻塞性肺病是可以治疗的,尽管它是一种慢性疾病,会随着时间的推移而恶化。此外,大多数慢性阻塞性肺病患者可以通过精心治疗改善症状调节和生活质量,并降低发生其他疾病的机会。因此,慢性阻塞性肺病诊断在早期阶段至关重要,因为它是可治疗的,并将对患者的健康恢复产生重大影响。高维生物医学数据中有成千上万的特征,准确有效地识别这些数据中的主要特征可能有助于识别相关疾病。然而,生物数据经常包含许多不相关或重复的特征,这严重影响了后期分类的准确性和机器学习的效率。因此,对于慢性阻塞性肺病的诊断,需要一个有效的预测模型。本文提出了一种混合特征选择模型,从高维数据中提取最佳特征。这些特征进一步传递给分类模型,以识别特征在各种分类模型上的性能。实验数据表明,所提出的混合特征选择模型预测COPD的准确率为95.18%,Kappa统计量为0.9。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Hybrid Feature Selection Model for Predicting Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) is characterized by a chronic airflow limitation that is generally progressive and an increased chronic inflammatory response triggered by harmful particles or gases in the airways. In general, symptoms, medical history, clinical examination, and lung ventilation obstruction play a vital role in diagnosis. However, COPD is treatable, even though it is a chronic condition that worsens over time. Furthermore, most patients with COPD can have improved symptom regulation and quality of life with careful treatment and a lower chance of developing other disorders. Therefore, COPD diagnosis is essential in the early stages, as it is treatable and will significantly impact the recovery of a patient's health. With tens of thousands of characteristics in high-dimensional biomedical data, precise and effective identification of the main characteristics in these data might help identify associated disorders. However, biological data frequently contains many irrelevant or duplicated characteristics, which significantly impact later classification accuracy and machine learning efficiency. As a result, for COPD diagnosis, an effective predictive model is needed. This study proposed a hybrid feature selection model to extract the best features from the high-dimensional data. These features are further passed to the classification models to identify the performance of the features on various classification models. According to the experimental data, the suggested hybrid feature selection model could predict COPD with a 95.18 percent accuracy and a Kappa Statistic of 0.9.
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