磁泳术用于单核细胞分离及单核细胞吞噬能力的诊断评价

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Pub Date : 1988-12-01 DOI:10.1109/IEMBS.1988.95127

H. Minamitani, T. Shimomura, M. Aiba, E. Okada

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引用次数: 0

摘要

作者讨论了磁泳术，该方法在直流磁场下特异性地从单核细胞悬浮液中分离出吞噬右旋糖酐铁微球。在单核细胞分离效率的基础上对肝病患者的吞噬能力进行诊断评价。磁分离结果表明，肝癌和肝硬化患者的吞噬能力明显低于健康志愿者。磁泳术是研究吞噬作用的必要条件。

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Magnetophoresis for mononuclear cell separation and diagnostic evaluation of the phagocytic capacity of monocyte

The authors discuss magnetophoresis, which specifically separates monocytes phagocytizing iron dextran microspheres from mononuclear cell suspensions under a DC magnetic field. Diagnostic evaluation of the phagocytic capacity was carried out for patients with liver diseases on the basis of the separation efficiency of the monocytes. Results of the magnetic separation showed that the phagocytic capacities of hepatoma and liver cirrhosis patients were significantly lower than those of healthy volunteers. Magnetophoresis was found to be essential in investigating the phagocytosis.<>

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Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society

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