[人乳头瘤病毒(hpv)的检测]利用分子杂交技术研究生殖器病变中的DNA。

S Meguenni, S el-Mehdaoui, D Bandoui, A Bouguermouh, A Allouache, A Bendib, A Chouiter, T Djenaoui, N Lalliam, A Bouhadef
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引用次数: 0

摘要

用分子杂交技术检测生殖器病变中人乳头瘤病毒。有些类型的hpv是通过性传播并感染生殖器官的。我们用分子杂交技术对344例患者的良性、癌前和恶性生殖器病变中hpvv 6或hpvv II和hpvv 16的分布进行了研究。hpv - 16阳性病例的频率随着宫颈病变向恶性发展而增加:癌中57/78(73%)为阳性,轻、中度发育不良中29/83(35%)为阳性。大多数良性尖锐湿疣含有其他类型的DNA,即hpv 6和II。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Detection of human papillomavirus (H.P.V.) DNA in genital lesions using molecular hybridization].

Detection of human papilloma virus in genitals lesions by molecular hybridization. Some H.P.V. types are sexually transmitted and infect genital organs. We have used molecular hybridization to examine the distribution of H.P.V. 6 or II and H.P.V. 16 in benign, premalignant and malignant genital lesions from 344 patients. The frequency of H.P.V. 16 positive cases increases as the cervical lesions progress to malignancy: 57/78 are positive (73%) in the carcinomas, 29/83 are positive (35%) in mild or moderate dysplasia. The majority of benign condylomata acuminata harbors DNA of other types, namely H.P.V. 6 and II.

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