{"title":"妊娠期急性脂肪肝的研究进展","authors":"P. Sinha, P. Kyle, P. Gubbala","doi":"10.5580/1d1d","DOIUrl":null,"url":null,"abstract":"Acute fatty liver of pregnancy (AFLP) is a serious complication and usually occurs in second half of pregnancy. It is rare but potentially fatal complication for both mother and baby as often the diagnosis is delayed. Etiology is still unclear but known to be associated with defective fatty acid oxidation in fetus. AFLP is thought to be a rare variant of pre-eclampsia (associated in 50 to 100% of cases) and can be associated with mild to moderate disease . It can cause multiple organ failure in case of delayed diagnosis. Early diagnosis and prompt delivery is the mainstay of treatment.","PeriodicalId":158103,"journal":{"name":"The Internet journal of gynecology and obstetrics","volume":"8 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2009-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Acute Fatty Liver of Pregnancy - A Review:\",\"authors\":\"P. Sinha, P. Kyle, P. Gubbala\",\"doi\":\"10.5580/1d1d\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Acute fatty liver of pregnancy (AFLP) is a serious complication and usually occurs in second half of pregnancy. It is rare but potentially fatal complication for both mother and baby as often the diagnosis is delayed. Etiology is still unclear but known to be associated with defective fatty acid oxidation in fetus. AFLP is thought to be a rare variant of pre-eclampsia (associated in 50 to 100% of cases) and can be associated with mild to moderate disease . It can cause multiple organ failure in case of delayed diagnosis. Early diagnosis and prompt delivery is the mainstay of treatment.\",\"PeriodicalId\":158103,\"journal\":{\"name\":\"The Internet journal of gynecology and obstetrics\",\"volume\":\"8 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-12-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Internet journal of gynecology and obstetrics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5580/1d1d\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Internet journal of gynecology and obstetrics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5580/1d1d","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Acute fatty liver of pregnancy (AFLP) is a serious complication and usually occurs in second half of pregnancy. It is rare but potentially fatal complication for both mother and baby as often the diagnosis is delayed. Etiology is still unclear but known to be associated with defective fatty acid oxidation in fetus. AFLP is thought to be a rare variant of pre-eclampsia (associated in 50 to 100% of cases) and can be associated with mild to moderate disease . It can cause multiple organ failure in case of delayed diagnosis. Early diagnosis and prompt delivery is the mainstay of treatment.
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