利用富含干细胞的自体骨髓作为骨诱导剂治疗上颌窦抬高

Ibañez Juan Carlos, Juaneda Maria Agustina, Ibanez María Constanza, Ibañez Santiago Luis
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引用次数: 0

摘要

目的:探讨以未经处理的自体骨髓与Bio-Oss(60:40)混合作为移植材料,采用压电手术行侧开窦提升术的结果,测量上颌窦内形成的骨组织数量、移植物获得的最终存活骨的百分比以及植入窦内的成功率。材料和方法:对13例患者(10例双侧,3例单侧)进行23例上颌窦提升,采用股骨远端骨髓混合异种移植物(Bio-Oss),所有病例均采用外侧窗窦提升技术,采用压片手术。放置并加载49个植入物。测量接枝体积、高度和密度。除新骨百分比外,还测量了生物材料残余和结缔组织的百分比。结果:平均体积1668 mm3,平均身高10.9 mm,骨密度648 HU。获得的新骨、残骨和结缔组织的比例分别为37.08、16.77和45.22。结论:使用Bio-Oss与股骨远端骨髓的混合物似乎是一种有效的组合,当进行窦提升时,可以获得足够比例的重要骨。此外,采用表面微织构的种植体进行此类鼻窦移植可取得良好的效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Use of autologous bone marrow rich in stem cells as an osteoinducer in maxillary sinus elevation
Aim: To study the results that can be obtained when performing sinus lift technique by lateral opening with piezo surgery using as graft material a mixture of autologous bone marrow without any treatment and Bio-Oss (60:40) measuring the amount of bone tissue formed in the maxillary sinuses, the percentage of final vital bone obtained in the grafts and the success rate of the implants placed in those sinuses. Materials and methods: 23 maxillary sinus lifting were performed in 13 patients (10 bilateral, 3 unilateral) using a mixture of bone marrow taken from distal femur with a xenograft (Bio-Oss) Lateral window sinus elevation technique using piezo surgery was used in all cases. 49 implants were placed and loaded. Graft volume, height and density were measure. Besides percentages of new bone, biomaterial remnant and connective tissue were also measure. Results : Mean volume obtained was 1668 mm3, mean height was 10.9 mm and bone density was 648 HU. Percentage of new bone, biomaterial remnant and connective obtained were 37.08, 16.77 and 45.22 respectively. Finally, the percentage of success of the implants inserted in these grafted sinuses was 96% Conclusions: The use of a mixture of Bio-Oss with bone marrow obtained from the distal femur seems to be an efficient combination to obtain an adequate percentage of vital bone when sinus lifting is performed. Besides good results can be achieved when implants with microtextured surface are used in this type of sinus graft.
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