斑点斑点法检测日本妇女正常宫颈中人乳头瘤病毒DNA。

J Saito, T Fukuda, H Nakatani, M Sumiyoshi, M Kinoshita, M Ikeda, K Noda
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引用次数: 0

摘要

采用点印迹法对9例宫颈上皮内瘤变(CIN)ⅰ型和ⅱ型患者、11例宫颈上皮内瘤变(CIN)ⅲ型患者、22例宫颈癌患者和599例宫颈细胞学正常患者(包括63例孕妇)的脱落宫颈细胞进行人乳头瘤病毒(HPV)检测。HPV感染在CIN I和II病例中占33.3%,在CIN III病例中占54.5%,在浸润性宫颈癌中占68.2%,在正常组中占4.2%。妊娠期间脱落的宫颈细胞中可检测到的HPV感染率增加。这些结果提示少数宫颈细胞学正常的日本妇女感染了HPV。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Detection of human papillomavirus DNA in the normal cervices of Japanese women by the dot-blot (Vira Pap) method.

Exfoliated cervical cells obtained from 9 patients with cervical intraepithelial neoplasia (CIN) I and II, 11 with CIN III, 22 with cervical carcinoma, and 599 with cytologically normal cervices (including 63 pregnant women) were evaluated for the presence of human papillomavirus (HPV) by the dot-blot (Vira Pap) method. HPV infection was detected in 33.3% of the CIN I and II cases, in 54.5% of the CIN III cases, in 68.2% of invasive cervical carcinoma cases, and in 4.2% of the normal group. The rate of detectable HPV infection increased in exfoliated cervical cells during pregnancy. These results suggested that a few Japanese women with cytologically normal cervices were infected with HPV.

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