Comparative evaluation of hydroxyapatite fluoride and casein phosphopeptide amorphous calcium phosphate fluoride as remineralizing agents in primary teeth using pH cycling and single-sectioning technique

Background: Hydroxyapatite and casein phosphopeptide-amorphous calcium phosphate are known to remineralize subsurface carious lesions. Aim: The aim of this study was to evaluate the effect of topical application of hydroxyapatite fluoride (HF) and caseinphosphopeptide-amorphous calcium phosphate fluoride paste (CPP-ACPF) in bringing about remineralization changes in artificially induced carious lesions of primary teeth using pH cycling and single-sectioning technique. Materials and Methods: Seventy extracted deciduous teeth were divided into two groups: Group A: HF (Remin Pro) n = 35 and Group B: CPP-ACPF (Tooth Mousse Plus®) n = 35. The samples were immersed in demineralizing solution for 96 h followed by pH cycling for 10 days which included cycles of demineralization and remineralization of their respective groups. Results: Intergroup comparison of the change in the mean value after demineralization and remineralization showed statistically highly significant difference as the change in Group A HF was 213.52 ± 113.17 (standard deviation [SD]) as compared to that in Group B (CPP-ACPF) 76 ± 57.22 (SD). Conclusion: HF was found to be better when compared to CPP-ACPF for tooth remineralization.