高脂血症和肝炎患者血清中特异二价微量元素水平的比较

H. Soran, Dler. M. Salh, A. Arif
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引用次数: 0

摘要

肝炎感染的患者也可能有高脂血症。肝炎(40例)和高脂血症(40例)血清采集于苏莱曼尼亚-库尔德斯坦地区/伊拉克中心实验室。采用计算机化数据库程序对患者的年龄、性别、感染持续时间、用药情况、血脂等特征信息进行统计。采用电感耦合等离子体发射光谱法(ICP-OES)测定两例患者血清中Cr、Cu、Zn、Mn、V和Se的水平,并与健康对照(n=30)进行比较。肝炎样品的浓度ppb分别为(7.34±0.01)Cr、(171.7±2.51)Cu、(138±3.41)Zn、(1.309±0.99)Mn、(184.7±6.12)V和(218.9±3.14)Se,高脂血症样品的浓度ppb分别为(5.22±0.45)Cr、(197.01±2.34)Cu、(160.3±4.01)Zn、(0.068±1.91)Mn、(247.01±0.65)V和(185.5±3.11)Se。对照样品的浓度分别为(ppm)(5.324±1.34)Cr、(131.2±4.34)Cu、(216.6±0.83)Zn、(0.024±1.75)Mn、(235.3±0.18)V和(223.2±3.15)Se。本研究的目的是评估金属离子在体内的生理作用,由于肝脏负责脂质合成,因此建议在研究过程中对脂质谱进行调查。关键词:肝炎;高脂血症;微量元素
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Compared Levels of Specific Divalent Trace Elements in Hyperlipidemia and Hepatitis Sera Patients
Patients with hepatitis infection can also have hyperlipidemia. Sera of both hepatitis (40) and hyperlipidemia (40) were collected from the central lab of Sulaimaniyah-Kurdistan region/ Iraq. Age, sex, duration of infection, medication used and lipid profile using computerized database program, as characteristics information of patients were done.  The levels of Cr, Cu, Zn, Mn, V and Se were determined in sera of both patients and compared with healthy controlled (n=30), using Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES). Hepatitis samples yielded concentration in ppb of (7.34±0.01) Cr, (171.7±2.51) Cu, (138±3.41) Zn, (1.309±0.99) Mn, (184.7±6.12) V and (218.9±3.14) Se respectively, while hyperlipidemia samples yielded concentration (ppb) of (5.22±0.45) Cr, (197.01±2.34) Cu, (160.3±4.01) Zn, (0.068±1.91) Mn, (247.01±0.65) V and (185.5±3.11) Se respectively. Controlled samples reflects the following concentrations (ppm),  (5.324±1.34) Cr, (131.2±4.34) Cu, (216.6±0.83) Zn, (0.024±1.75) Mn, (235.3±0.18) V and (223.2±3.15) Se  respectively.The aim of the study focused on evaluating metal ions physiological role in the body, and as liver was responsible for synthesizing lipid , thus lipid profiles where suggested to be investigated along the study. Key words: hepatitis, hyperlipidemia, trace elements, ICP-OES technique
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