用于内部辐射源蒙特卡罗分析的高分辨率拟人化幻影

I. Zubal, G. Gindi, M. Lee, C. R. Harrell, Eileen O. Smith
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引用次数: 31

摘要

一个与典型男性解剖结构非常相似的数字体素幻影已经被创造出来。在人体躯干的78个横截面上,以1毫米的分辨率手工绘制器官轮廓。这种拟人化的三维幻影在放射科学中有几个有趣的应用。蒙特卡罗模拟可以产生新的研究放射性药物的诊断真实图像。从小动物实验中近似获得的摄取特性可用于测试人体几何图形的成像特性。得到的图像可以作为已知源和衰减器分布的理想投影数据。这可以更好地理解临床真实模型的图像形成过程,并且可以证明在测试和改进层析成像重建算法方面特别有趣。使用该模型计算内部和外部辐射源的剂量可以在健康物理和治疗领域提供新的见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
High resolution anthropomorphic phantom for Monte Carlo analysis of internal radiation sources
A digital voxel phantom which closely resembles a typical male anatomy has been created. Organ outlines were manually drawn with 1-mm resolution in each of 78 transverses of the human torso. Such an anthropomorphic three-dimensional phantom has several interesting applications in the radiological sciences. Monte Carlo simulations can yield diagnostically realistic images of new investigational radiopharmaceuticals. Uptake characteristics approximated from small animal experiments can be used to test the imaging characteristics in human geometries. The resulting images can serve as ideal projection data of known source and attenuator distributions. This can lead to a better understanding of the image formation process for clinically realistic models, and can prove especially interesting in testing and improving tomographic reconstruction algorithms. Dose calculations for internal and external radiation sources using this phantom can give new insights in the field of health physics and therapy.<>
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