{"title":"脊髓刺激中侧支对背柱纤维兴奋阈值的影响","authors":"J.J. Struijik, J. Holsheimer, H. Boom","doi":"10.1109/IEMBS.1991.684256","DOIUrl":null,"url":null,"abstract":"In this paper we present the effect of epidural spinal cord stimulation on myelinated dorsal column nerve fibers. An important feature of these fibers is the presence of collaterals perpendicular to the main fibers. In order to investigate the behavior of these fibers in spinal cord stimulation, we first calulated the potential field in the spinal cord, using a realistic volume conductor model. Second, this field was applied to an electrical network model of the fibers. It is concluded that both excitation threshold and blocking threshold of dorsal column nerve fibers are decreased by 30-50%, compared to thresholds of simple straight fibers.","PeriodicalId":297811,"journal":{"name":"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Volume 13: 1991","volume":"29 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1991-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effect Of Collateral Branching On Excitation Threshold Of Dorsal Column Fibers In Spinal Cord Stimulation\",\"authors\":\"J.J. Struijik, J. Holsheimer, H. Boom\",\"doi\":\"10.1109/IEMBS.1991.684256\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this paper we present the effect of epidural spinal cord stimulation on myelinated dorsal column nerve fibers. An important feature of these fibers is the presence of collaterals perpendicular to the main fibers. In order to investigate the behavior of these fibers in spinal cord stimulation, we first calulated the potential field in the spinal cord, using a realistic volume conductor model. Second, this field was applied to an electrical network model of the fibers. It is concluded that both excitation threshold and blocking threshold of dorsal column nerve fibers are decreased by 30-50%, compared to thresholds of simple straight fibers.\",\"PeriodicalId\":297811,\"journal\":{\"name\":\"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Volume 13: 1991\",\"volume\":\"29 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1991-11-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Volume 13: 1991\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/IEMBS.1991.684256\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Volume 13: 1991","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IEMBS.1991.684256","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effect Of Collateral Branching On Excitation Threshold Of Dorsal Column Fibers In Spinal Cord Stimulation
In this paper we present the effect of epidural spinal cord stimulation on myelinated dorsal column nerve fibers. An important feature of these fibers is the presence of collaterals perpendicular to the main fibers. In order to investigate the behavior of these fibers in spinal cord stimulation, we first calulated the potential field in the spinal cord, using a realistic volume conductor model. Second, this field was applied to an electrical network model of the fibers. It is concluded that both excitation threshold and blocking threshold of dorsal column nerve fibers are decreased by 30-50%, compared to thresholds of simple straight fibers.