耳部分泌物病原体的抗生素耐药性:一个耳聋问题

Dr. Gulsiv Nair, Dr. M Lakshminarayana, Dr. Lavanya Nagaraj, D. M., D. Sa
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引用次数: 0

摘要

耳内分泌物是常见的,由于抗菌素耐药性的增加,其管理变得复杂。对2018年6月至2019年5月在爱资哈尔医学院微生物实验室收到的耳部分泌物样本进行处理,鉴定微生物并进行药敏试验。优势菌为铜绿假单胞菌(24/53,45.28%)。对氟喹诺酮类药物(91.67%)和氨基糖苷类药物(95.83%)的敏感性较好。革兰氏阳性11株,其中金黄色葡萄球菌8株,凝固酶阴性葡萄球菌3株。5株为MRSA(62.5%)。对氨苄西林(27.27%)、阿莫昔拉夫(36.36%)、第三代头孢菌素(54.55%)、阿奇霉素(54.55%)和氟喹诺酮类药物(45.45%)的敏感性令人失望。复方新诺明的敏感性为72.73%。7株为肠杆菌。对氨苄西林、阿莫昔拉夫、头孢呋辛和大环内酯类药物的敏感性均为14.29%。头孢曲松和复方新诺明的敏感性为57.14%。氟喹诺酮类药物敏感性较差(71.43%)。基于微生物学证据的抗菌治疗对于面对高抗生素耐药性的管理至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antibiotic resistance in causative agents of ear discharge: A deafening problem
Discharge from the ear is common, the management of which is complicated by rising antimicrobial resistance. Ear discharge samples received at the microbiology laboratory in Al Azhar Medical College from June 2018 to May 2019 were processed, and organisms identified and susceptibility tested. The predominant organism was Pseudomonas aeruginosa (24/53, 45.28%). The susceptibility of these isolates to fluoroquinolones (91.67%) and aminoglycosides (95.83%) was good. Eleven isolates were Gram positive, with 8 Staphylococcus aureus and 3 coagulase negative Staphylococcus. Five isolates were MRSA (62.5%). Susceptibility to ampicillin (27.27%), amoxiclav (36.36%), 3 rd generation cephalosporins (54.55%), azithromycin (54.55%), and fluoroquinolones (45.45%) was disappointing. Cotrimoxazole susceptibility was 72.73%. Seven isolates were Enterobacterales. Susceptibility to ampicillin, amoxiclav, cefuroxime and macrolides (each 14.29%) was alarming. Ceftriaxone and cotrimoxazole showed susceptibility of 57.14%. Fluoroquinolone susceptibility (71.43%) was also poor. Antimicrobial therapy based on microbiological evidence is essential for the management in the face of high antibiotic resistance.
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