Influenza virus detection technology based on organic electrochemical transistor

Influenza results in massive casualties and property loss each year due to the high infectivity and multiple variation of its virus. Thus, early diagnosis of influenza viruses plays a crucial role, however rapid an on-site detection can hardly be achieved currently. Organic electrochemical transistor (OECT) has the characteristics of high sensitivity, fast response speed and good biocompatibility, and has been widely used in the detection of DNA and protein. In this work, we developed an OECT-based influenza virus sensor. Through the detection of HA peptide antigens, it shows that the sensor has a detection limit of less than 10-9M.