高通量筛选中斑马鱼体细胞的自动定量

2006 IEEE/NLM Life Science Systems and Applications Workshop Pub Date : 2006-07-13 DOI:10.1109/LSSA.2006.250389

Jianfeng Lu, Tianming Liu, Jingxin Nie, Jie Ding, Jinmin Zhu, Jingyu Yang, Lei Guo, W. Xia, Stephen T. C. Wong

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引用次数: 4

摘要

随着高通量成像仪和大量斑马鱼胚胎的可用性，斑马鱼是迄今为止最具成本效益的脊椎动物系统之一，用于高通量或高含量的筛选。随着大量斑马鱼产生的大量图像，计算机图像分析对于准确有效的数据解释变得至关重要。本文提出了一种在高通量筛选中自动定量斑马鱼体的算法。初步的评估结果证明了该算法的性能。该算法已集成到我们的CBI平台中

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Automated Quantitation of Zebrafish Somites in High-Throughput Screens

With the availability of high-throughput imaging machines and large number of zebrafish embryos, zebrafish is by far one of the most cost-effective vertebrate systems for high-throughput or high-content screens. With the tremendous amount of images generated from large numbers of zebrafish, computerized image analysis for accurate and efficient data interpretation becomes essential. This paper presents an automated algorithm for quantitation of zebrafish somite in high-throughput screen. Preliminary evaluation results are shown to demonstrate the performance of the algorithm. This algorithm has been integrated into our CBI platform

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2006 IEEE/NLM Life Science Systems and Applications Workshop

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